ID   A0A093Z5M2_9PEZI        Unreviewed;       320 AA.
AC   A0A093Z5M2;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Methyltransferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=V491_07740 {ECO:0000313|EMBL:KFY10273.1};
OS   Pseudogymnoascus sp. VKM F-3775.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420901 {ECO:0000313|EMBL:KFY10273.1, ECO:0000313|Proteomes:UP000029338};
RN   [1] {ECO:0000313|EMBL:KFY10273.1, ECO:0000313|Proteomes:UP000029338}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-3775 {ECO:0000313|EMBL:KFY10273.1,
RC   ECO:0000313|Proteomes:UP000029338};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-methionyl-[protein] + S-adenosyl-L-methionine = S-adenosyl-
CC         L-homocysteine + S-methyl-L-methionyl-[protein];
CC         Xref=Rhea:RHEA:60560, Rhea:RHEA-COMP:12313, Rhea:RHEA-COMP:15592,
CC         ChEBI:CHEBI:16044, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:142742; Evidence={ECO:0000256|ARBA:ARBA00036003};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:60561;
CC         Evidence={ECO:0000256|ARBA:ARBA00036003};
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. LaeA
CC       methyltransferase family. {ECO:0000256|ARBA:ARBA00038158}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY10273.1}.
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DR   EMBL; JPJT01004722; KFY10273.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093Z5M2; -.
DR   HOGENOM; CLU_010595_2_0_1; -.
DR   Proteomes; UP000029338; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43591; METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43591:SF30; PROTEIN-METHIONINE METHYLTRANSFERASE LAEA; 1.
DR   Pfam; PF13489; Methyltransf_23; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000029338}.
SQ   SEQUENCE   320 AA;  36955 MW;  9771C3B611259B56 CRC64;
     MAVKFPDHEE NGRIYHGFRR GIYMFPCDEA EQDRMDIFHK FFNVARQGVL HSAPFTPNDD
     GHRVLDLGTG TGIWAIDMAD KYPEAEVMGF DISLIQPQSI PPKLQFRRRD FETTWCGLAM
     DSYDLIHLRM LAGSISSYPE LYANIIQYDR DLKHGIGLLL TYFSRHVKPK YGWIEHVEID
     FAPKCDDGSL PRDAALVDWL DLLMDATEEA CKPLAYNTET EAMLQKAGFV EVTEQVIKIP
     FNCWPSDTHQ KDIGAWFSLG LSQGLEALTL GPLTRIRHWD REAVEELVAK VKRDIRTEKY
     HVYCEMHIWT ARRPENAMEK
//