ID A0A094A1W4_9PEZI Unreviewed; 924 AA.
AC A0A094A1W4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Anaphase-promoting complex subunit 2 {ECO:0000256|ARBA:ARBA00016068};
GN ORFNames=V493_05724 {ECO:0000313|EMBL:KFY23646.1};
OS Pseudogymnoascus sp. VKM F-4281 (FW-2241).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420906 {ECO:0000313|EMBL:KFY23646.1, ECO:0000313|Proteomes:UP000029327};
RN [1] {ECO:0000313|EMBL:KFY23646.1, ECO:0000313|Proteomes:UP000029327}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4281 (FW-2241) {ECO:0000313|Proteomes:UP000029327};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY23646.1}.
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DR EMBL; JPJV01002213; KFY23646.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094A1W4; -.
DR STRING; 1420906.A0A094A1W4; -.
DR HOGENOM; CLU_007149_0_0_1; -.
DR OrthoDB; 2786196at2759; -.
DR Proteomes; UP000029327; Unassembled WGS sequence.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044554; APC2-like.
DR InterPro; IPR014786; APC2_C.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45957; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR45957:SF1; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR Pfam; PF08672; ANAPC2; 1.
DR Pfam; PF00888; Cullin; 1.
DR SMART; SM01013; APC2; 1.
DR SMART; SM00182; CULLIN; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000029327};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 581..803
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 21..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 830..850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 924 AA; 103596 MW; 52A4F9D23EE9E97A CRC64;
MGVKARERQV FNSVFEKYAV SVSEPTPKST PSTGFTAPGQ PFGGPRSSGN QHLAGRGSEY
QPPSDTRSDS SRHVQDQVTW DRSWHVVTSW LSFQNEPFSP YGQEIHRAEK ASPPLKYGTA
LLDVLTPETR LPYAAHHENL VKWLSQNMRS HFFRTVQPWL ENAVTGFSHE ELLQRILQVL
VQAQSLYLDK VTEIEKTLSH RSSSLPESFK GGFHRDFEAL VRKSVPESVW ETVEWYVNRE
IPIVLAVPRV VDGTRISPDR MEQEEARSKL LALAQALRNV GLGGERFQIM FAEAMNASMS
TYVYGTYQRV WKDEPSPPNP AEVKKRRKSQ HFWSSLVGPS SLSAEDEPLV PRVVNYSNPS
RCVTDLCAWT ENEYARLAVE ILSQLDSTEV AYSDLEKWKE MAIGRLASLR TSELFDIVVH
WPNGGGAIDD LRTAITTPQR RLQLTEAFTV ELKERLLHPG KSTLEILRTY IAMICSFHAL
DHSKVLLDRV AYPLQVYLCS REDTVRIIIT GLLADKDVEK GKPSSSNGEK LVELAYLLNS
GVDSAQGPDD DMDWNDMEWV PDPVDAGPGY KRRKNVDIIG TLIGVLGSQD VFIKEFQSII
GDNLLKNDGD FDREIKVLEL LKTRFGESSL QSCEVMIKDI QDSRRLNGAI RRAQKLEPSA
EEITTASLHT LRTAQDDMSP EGLLKPSLHA KILSRLFWPQ LQDETYKVPD PIAHLQQRYE
AGFESLKNAR KLAWLHALGH ATVDIELEDR TITEVVHTYQ AAVIWAFQGA PQGAEPVSRS
FEYLAEHLQM DDALLRPALA FWVGKMVLHS PRPDEFAVLE TLNPAERQRS DAAAAAAAAG
GSADDGPARG APAEDKMAMY WKFIQGMLKN SAAKMPLAQI GMMLKMLIVE GFPYSNEELA
EYLATKVATG ELELAGGKYR LVKK
//
