ID A0A094AM16_9PEZI Unreviewed; 665 AA.
AC A0A094AM16;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 13-SEP-2023, entry version 39.
DE RecName: Full=Alpha-actinin {ECO:0008006|Google:ProtNLM};
GN ORFNames=V490_01962 {ECO:0000313|EMBL:KFX99081.1};
OS Pseudogymnoascus sp. VKM F-3557.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1437433 {ECO:0000313|EMBL:KFX99081.1, ECO:0000313|Proteomes:UP000029320};
RN [1] {ECO:0000313|EMBL:KFX99081.1, ECO:0000313|Proteomes:UP000029320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-3557 {ECO:0000313|EMBL:KFX99081.1,
RC ECO:0000313|Proteomes:UP000029320};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the alpha-actinin family.
CC {ECO:0000256|ARBA:ARBA00010255}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFX99081.1}.
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DR EMBL; JPJS01000545; KFX99081.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094AM16; -.
DR STRING; 1437433.A0A094AM16; -.
DR HOGENOM; CLU_005217_0_2_1; -.
DR Proteomes; UP000029320; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd21215; CH_SpAIN1-like_rpt1; 1.
DR CDD; cd21291; CH_SpAIN1-like_rpt2; 1.
DR Gene3D; 1.20.58.60; -; 2.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR014837; EF-hand_Ca_insen.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF08726; EFhand_Ca_insen; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM01184; efhand_Ca_insen; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 2.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000029320};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 11..116
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 125..231
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 485..520
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 646..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 665 AA; 75925 MW; FF60D31EF332AD04 CRC64;
MAYAEQHKWI NVQQKTFTKW LNAKISAREV EVKDLVKDLS DGVILIHLLE CLSSESLGRY
AAKPKLRVQR FENANLSLDF IKSKGIQMTN IGAEDVVDGN RKIILGLIWT LILRFTISDI
NQEGMTAKEG LLLWCQRKTA CYDEVEVRDF SGSWNDGLAF CALLDIHRPD LIDYDALDKN
DHRGNMQLAF DIASKEIGIP DLLDVEDVCD VAKPDERSLM TYIAYWFHAF SQMEKVENAG
RRVEKFVSSM QGAWEMQSAF ERRMRALLKA IKEQGQSWQD SDFEGTYVDA KLQSSEFGAY
KRGQKRQWVA EKSELAALLG NIKTKMSTYR LRPYDPPQEL RLDTLEKEWA VLMRAEMARG
QLINETIRDI KNALRRTFAD KANDFALALN AMQLAVSGLE GDVEDQLRHV KRLNESVAPL
DSYLETIAEL DQKCEEANIE ENDFTTYTYD ELSYELGLVK GSVSKKLAFL DNQVVARNMT
NLTPIQLEEF ESVFRHFDRD ASNSLQELEF SAALASLGLV FSEDEMHDYF LETSHGRDHV
TFEQFINFMV DVTEDQNTAE QVFQSFREVA DGKPYVTEMD LRHSLVPDDV IEKLTKIIPA
HKGPDLQEDR GMPQYDYVSF MDHLIDDPEE ELRTEAGKGT KVLGEIQNTP GVKAHASPTK
SNGNY
//
