ID A0A094AVP7_9PEZI Unreviewed; 616 AA.
AC A0A094AVP7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=AMP-dependent synthetase/ligase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=V493_03655 {ECO:0000313|EMBL:KFY27205.1};
OS Pseudogymnoascus sp. VKM F-4281 (FW-2241).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420906 {ECO:0000313|EMBL:KFY27205.1, ECO:0000313|Proteomes:UP000029327};
RN [1] {ECO:0000313|EMBL:KFY27205.1, ECO:0000313|Proteomes:UP000029327}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4281 (FW-2241) {ECO:0000313|Proteomes:UP000029327};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY27205.1}.
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DR EMBL; JPJV01001407; KFY27205.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094AVP7; -.
DR STRING; 1420906.A0A094AVP7; -.
DR HOGENOM; CLU_000022_59_2_1; -.
DR OrthoDB; 1404660at2759; -.
DR Proteomes; UP000029327; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR CDD; cd05911; Firefly_Luc_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24096:SF149; 4-COUMARATE--COA LIGASE 1-RELATED; 1.
DR PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029327};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 87..464
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 515..595
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 616 AA; 68325 MW; 1EE128EA5E24CBC0 CRC64;
MDLRSKLLDV ASGIALSCIV TFVLNIYIPW APDLDIYLFI VIIIFNSAQF CSPDIKPSPT
RRPIIMVTKS SFPDIDVPAV DVWGLLFERK DKKFSDNKVI YVDPETNRSY TFAETKKAAI
EFGKGLKAQW DWKKGDVLAL YTPNSIDTPA VIWGTHWAGG VISPANPAYT PAELAFQLKD
CGAKALVTQR AFLADARAAA KSVGLPEKRI IILGDERDEL FKHFTSIRNI SGATRYARTR
VNPETDLAFL VYSSGTTGHP KGVMLSHRNI VSNLFMLAAG EGNNLSSEGG PDGKGDKLLA
FLPFFHIYGL TCLIHYAFFR GLTIYVMAKF DLERFCSIIQ ENKITFAYAV PPVVLQLAKN
PVVDKYDLSS VRMMSSGAAP LTREIVNALY AKRNIKVKQG YGLSETSPTT HSQRWEDWQT
AMGSVGPLLP NQTAKFMSPE EKELEVGETG ELWVKGPNVF MGYWKNPEGT KNALTDDGYF
KTGDVGFQDK KGNFYITDRV KELIKYKGFQ VPPAELEGLL VSHPHVDDVA VLGIYNEEQA
TEVPRAYVVP KNGVPGTPET GKNIADWLAT KVAGHKRLRG GVRFVDVIPK TASGKILRRV
LKQQAEAEEK MVKSRL
//
