ID A0A094C1W8_9PEZI Unreviewed; 2416 AA.
AC A0A094C1W8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY41450.1};
GN ORFNames=V494_02997 {ECO:0000313|EMBL:KFY41450.1};
OS Pseudogymnoascus sp. VKM F-4513 (FW-928).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420907 {ECO:0000313|EMBL:KFY41450.1, ECO:0000313|Proteomes:UP000029288};
RN [1] {ECO:0000313|EMBL:KFY41450.1, ECO:0000313|Proteomes:UP000029288}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4513 (FW-928) {ECO:0000313|Proteomes:UP000029288};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY41450.1}.
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DR EMBL; JPJW01000993; KFY41450.1; -; Genomic_DNA.
DR STRING; 1420907.A0A094C1W8; -.
DR HOGENOM; CLU_000022_31_4_1; -.
DR OrthoDB; 5396558at2759; -.
DR Proteomes; UP000029288; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd05195; enoyl_red; 1.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775:SF18; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF08659; KR; 1.
DR Pfam; PF21089; PKS_DH_N; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF14765; PS-DH; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00826; PKS_DH; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SMART; SM00822; PKS_KR; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000029288};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 38..472
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 2329..2409
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 71..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2416 AA; 263035 MW; D91068D3B4E1BC3E CRC64;
MTSGSSLSSE GYADIATPGT EKCSSDDGET FTPHHGTQVP IAIVGMGCRL PGHSNSPTAL
WDLLERGGVA KTQPPPSRFS LAGHYDKDNP QRPRTMKSPG GMFMEDVDPA LFDGQFFNIS
RTECIAMDPQ QRQMLEVAYE CLENSGTPME SLSGTNTGVI VGTNFIDYGA IQHRDPENRA
ESVMIGLAPA LLSNRISHFL NIHGPSMTVD TACSAGLVSL DVACRYLDSF QTDAVLVGSA
NLWLSPEHNE EIGMMHVTQS GSGLSKSFDA SADGYVKAEG VNCFYLKRLD DAVRNGDPIR
AIIRGTAVNA SGRTNGIANP SSDAQAAVTR QALKNANIKE KDFSKTRFLE AHGTGTLAGD
PIEARGAASV FSKGREDDQE LIIGSIKSNI GHSEPSAGLS GLLKATMAVE KGVIPGTPTF
FNPNPNIDWK SLRLKASRMS IPWPKVDADN IRRAGVNSFG YGGANAHAVV ENDAQELSRH
VSSYKQVTTD FFDDDDDDEF DEEQDSETQA APTLLFFSAN DQSSLDEYIK RFSSHLQNPV
VSLELGDLAY TLSERRSRHY QGAVAITRSN PQYINQETLI RGKRMSTVPR VAFVFTGQGA
QWPTMGADLI RDFPLAKSTV EYLDSVLQSL PSPPQWSLLE ELTATRSVEA LRLPEFSQPL
VTALQIALLR VLEEWGIFPE AVVGHSSGEI AAAYAANLLS SSDAIKVAYY RGQSSKKIQS
GDPVGMLATG IDEATLAGYL EQKENKIQIA CYNSPSSLTL SGLVSELEEL RDRIQADGHF
ARLLLVDLAY HSNYMAEIGE VYEGMLHEDG LFQQSATDRP KKSKTVAMFS SVTSAVIDPN
TTLDAAYWKK NMVSPVQFAA ATAELLKQSN ADFLIELGPS NALAGPIAQI KKALGKNGQY
ASALKRNNDS TVPMYEAAAR LFLAGDQQVS LAKVNRVNPQ TSKVIVDLPN YVWNHSTRYW
HETRASKEWR FKKFIHHDLI GSKVSSVGWN APIFRGNIRL AYMPWLRDHK LGTDVVFPAT
AYIAMAVEAM YQTAMVTKWK QNPPARYRFR LRDVKFLRAL VLAEERETTV SLSLTPVRGG
STASWYEYQM CSEQDGVDVD FVHSTGMVCV ETDYNDTPKS VEPLELATSA RLWYKTMAQM
GYNFGPSFQK HISVESTMGQ RQNRSTINLE PPPSQPEGQS WYPLHPAVLD GCFQATTPSL
WKGHLPQAGD PALVPKAIES VLIESGSARK SRVPTEGVAY ASANYLGAGD VESARNYSTN
VDLHDPLDGA LLFQLKGLAW TEMETSDEEK VPHQFMHVNW NADIDMLMES EPTSSTTWLG
SKTVQQVIDL VAHKSPELNV LEINLSLLDG SNLWLEQGKD ETDNPVRAGC SQYHFAVRDP
KTLIQAQEIF NSRALSPQFH LVMDVTKPIT ITEADSIDLA IINPGQDDLV EVDGLLQSLA
LTVRDGGFII SSGFAHIDSL GKTIHLSNGV SICRVAKQTE TALTIDGEAE VPPRNVTQVS
ILDAAAQVSI SEEVSKVRDG LATQKWLIEH SSNPLEEISS NTGVVIVLDE LFSSVMESID
AKQWELLQHL SKVQRPLLWV TSRSTDPTRA AAVGFLATIR AEEQVPFFTL DVEASTDRTI
ADAISACLGR VWDMTSAKTF DSRASIDYDF VERGGIVFVS RVYRDTSLTF GQSTHPSDRK
TEIVDLHKSD TLIKARCERL GNLDSVHFGE VNAEPSTLPD GLVEVEIHAA GISYKDVVVT
LGTAPGDETA LGNEAAGVVT KVAQGVSGLS VGDHVVVFDK GCFANRIHTR PGRIHRIPDS
MTFEEAATIP TAYITAIHAL LDHARLSVGQ KVLIHSAAGG VGIAAIQIAQ SVGAEVYATV
GTPEKKEFLK STFGLAEDRI FHSRSTEFGD QVLSATNGRG VDVILNSLTG DVLDESFRVL
ADGGIMVELG KRDVLDRNSL PWAPFDRNSS FRAIDLSPEK VTESLVARLM SKLFELIDGG
SIKPIAPVHK FAWNDIPAAF HFLRPGTHIG KVVLTQDSGS EVSIRRAPKS LNLRADGCYL
IVSSLRGLCG GLAIYLAQQG AKHLAVMSRS GYADEKSRLA IKQITALGCH IDLLVADVTN
ADAVTEAMKQ TTVPIVGIIQ GAMVLRDRPF ESMTLTEYHE ALQCKIRGTW NLHNASESLQ
LKLDSFTMLS SLSGIIGHVA QANYAAGNVF LDAFAAWRQN RGLPACSIDL GISEDSGVIA
ESAKLQSSTE KGMFRSLNEG QLRKILYFAM LQQKTTPLAG NVGIASELAF SPLITGLTFP
QPDDSILKSD ARFSPLFNNN GGPKDQKSSG ENASADIQAF FLLLRTESAD PASRLKALID
VINGCFMRIL RLDEPMDPER PTSVYGTDSL AAVEIRNWVR TELGCLVTTL DIMTATSLTS
FCEKILTKLS AAETAS
//
