ID A0A094CX25_9PEZI Unreviewed; 1191 AA.
AC A0A094CX25;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Rab-GAP TBC domain-containing protein {ECO:0000259|PROSITE:PS50086};
GN ORFNames=V497_08819 {ECO:0000313|EMBL:KFY51835.1};
OS Pseudogymnoascus sp. VKM F-4516 (FW-969).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420910 {ECO:0000313|EMBL:KFY51835.1, ECO:0000313|Proteomes:UP000029268};
RN [1] {ECO:0000313|EMBL:KFY51835.1, ECO:0000313|Proteomes:UP000029268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4516 (FW-969) {ECO:0000313|Proteomes:UP000029268};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY51835.1}.
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DR EMBL; JPJZ01001562; KFY51835.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094CX25; -.
DR STRING; 1420910.A0A094CX25; -.
DR HOGENOM; CLU_007428_0_0_1; -.
DR OrthoDB; 5472962at2759; -.
DR Proteomes; UP000029268; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22455; KH-I_Rnc1_rpt1; 1.
DR CDD; cd22456; KH-I_Rnc1_rpt2; 1.
DR CDD; cd22457; KH-I_Rnc1_rpt3; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 3.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR InterPro; IPR049786; Rnc1_KH-I_3.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR PANTHER; PTHR10288:SF142; RNA-BINDING PROTEIN PASILLA; 1.
DR Pfam; PF00013; KH_1; 3.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00322; KH; 3.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 3.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50084; KH_TYPE_1; 3.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029268};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 35..306
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT REGION 380..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 659..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 704..726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1050..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..645
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..689
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1083..1103
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1191 AA; 130424 MW; 9E922D77FFE338B4 CRC64;
MRSLDESRQR WQKTVEGASK VGGLRGLVKP NTDSICESGL RSVCWKVFLL FRSVDHNTWA
ATSEDSRAAY SALKSHFLRF IERPGDLDST IDPLNDDDNS PWNTLRRDEQ LCIEIAQDVE
RCMPEEPYFR LPETQKTLLQ ILFIYCKINQ DIGYRQGMHE LAAPILLAVQ RDALEPKAPD
GPKPSDDGDC LMSNMLDASF TEHDSFTLFN LIMRTAKSFY ELGEPDKRLN AGPTSSAQYG
SSPIVQRSKQ VHEVLLAQVD PELASHLTQI DILPQIFLIR WIRLLFGREF PFEDLLALWD
KLFAEDPDLE LIDMICVSML LRIRWQLLDA DYSVALTLLL KYPQPTPLYG PQTFVEDAVY
LRENLNEASG ARLINKYTGR PPVPLSSRPV PATPAGRPKA HRAESKFSGR KSPLPSPARF
LQEQRGMDLL QGAAKGVFER GERLGINQVV RDAVEEVKKN MQGLSPGPGS PRRASRNNAL
SVDEAVIVAE KSLADFEVRN KTLALLLSGT IEEIQKASDS TEDSSTKSTS VNKAIEKLRF
IMLRLEDSSL PLQPDTPRTA QDVEVAGTTR PEEKPRSEAG DAVMPPDPEK SIEAASSEVE
PLSPAAGSSP RLGRSIPRRP RTSVTKPPEA LNAESSNSGQ PAVGIPARST LAQSSFAWML
GPDEHSGPSD QSTSMKSSAP FLSSSRKAGS SAARERSAFL FGDDADEDDV NSQASPIRGG
NKTHTAFRAG TGEASTAQYG NSSSVSLSVT PPPPHLFFTS SFFLFSHHPP PPPLRPLPTP
SNRTPHRHLS PTHFLRPKID ILDTPAYYQL DSTLPQPQSN LHHHFKMSQQ DTRDQSGAED
VVDAMDRLNV DGERLGPDGE PAPKTEEDYA IAQLTLRAIV SSKEAGVIIG KAGKNVADLR
DETGVKAGVS KVVQGVHDRI LTITGGCDAI SKAYAIVAKA LLEGAPMMGM GGLVSTTGTH
PIKLLISHNQ MGTIIGRQGL KIKHIQDVSG VRMVAQKEML PQSTERIVEV QGTPEGIQKA
IWEICKCLID DWERGTGTVL YNPVVRTQTG GGQGGIRNEG REYSSPRVMR TGNGADFSQE
APRTFNRRSD GETAGRGVPT HDENGEEIQT QNISIPSDMV GCIIGRGGSK ISEIRKTSGA
RISIAKAPHD DTGERMFTIM GSAKANETAL YLLYENLEGE KMRRSQGNAQ E
//
