ID A0A094DAG5_9PEZI Unreviewed; 810 AA.
AC A0A094DAG5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 30.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0000259|SMART:SM01340};
GN ORFNames=V497_06209 {ECO:0000313|EMBL:KFY56455.1};
OS Pseudogymnoascus sp. VKM F-4516 (FW-969).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420910 {ECO:0000313|EMBL:KFY56455.1, ECO:0000313|Proteomes:UP000029268};
RN [1] {ECO:0000313|EMBL:KFY56455.1, ECO:0000313|Proteomes:UP000029268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4516 (FW-969) {ECO:0000313|Proteomes:UP000029268};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY56455.1}.
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DR EMBL; JPJZ01001092; KFY56455.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094DAG5; -.
DR STRING; 1420910.A0A094DAG5; -.
DR HOGENOM; CLU_011171_4_0_1; -.
DR OrthoDB; 1369806at2759; -.
DR Proteomes; UP000029268; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF41; MISMATCH REPAIR PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05820)-RELATED; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Reference proteome {ECO:0000313|Proteomes:UP000029268}.
FT DOMAIN 216..359
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT REGION 429..459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 548..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..623
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 810 AA; 87936 MW; EB0CF6EA5D40780D CRC64;
MAILPLPSST TRILGSCQAL TTPSSLVKEL IDNAIDAKAT SIDVIISANT VDKIEVHDNG
HGIAQEDLDS LGRHGHTSKL RNFEELRIVG SSCLGFRGEA LASSVSLGSV TITTRAEGEP
VAFVVKLKAT GGVSSKSSIS HPIGTTVCVS NFLSAFPVRR QTSIGDATRT ISKIKSILQS
YALARLQLRF TLKVAKTGKG NWSYIPHPKG HIKEAVMQVA GKEVAKQCFE ISSPIEDNAP
IFDAIDEYDP AASPFTGIRA FLPRPDSNFS KLKGGQYASV DSRPVSCARG TLKKVMASYK
QHIRAFVAKT GNEAPKDPFI YLNIACPIGS YDPNIEPAKD DVLFEDEEAI ISVADKLFKS
IYSTNTIPGE DTFHGLPAPK SGAAKNSAIQ QRLEVPKRVG ATDFRTPGVD YEPRDRQGQA
SISIDAAVDK TPGRESPDIL KGVDCEPQSP PGSLERSDHN SLNPWIIAKL NTPVTNNRAQ
SFKFLTPEPP GQYIPPIDGT PPASTDDVLL SGHLSGRSAA GQSWKQSRSG PTQSSVETWI
NKQQTYVIND SPEPRNSPEP QPPCHAIQGN SLPRHHYELP RSNGFVSVRT LPIDLPWSPP
PTQIRSKETP RRNFNTPFTT PKRTEIQPEG ALFTSSQELP GTSSSGFHNN VDAALDFEIR
KVASTRRLRE ETAAVARLEA KADDVVTDRM PDQKNILKTT LEDSDPRAYL MRRQKSMAAY
LNGPQQGPKL KRAKTMLLPL ESISTTLSTH NLIFRVSVET ASVTKAMHLL STVDDYARSG
TRCEGLVMTD SGAKEVEKAL NTLMAASLGH
//
