ID A0A094E1R6_9PEZI Unreviewed; 972 AA.
AC A0A094E1R6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=GPI ethanolamine phosphate transferase 3 {ECO:0000256|ARBA:ARBA00020841};
GN ORFNames=V499_07365 {ECO:0000313|EMBL:KFY72499.1};
OS Pseudogymnoascus sp. VKM F-103.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420912 {ECO:0000313|EMBL:KFY72499.1, ECO:0000313|Proteomes:UP000029295};
RN [1] {ECO:0000313|EMBL:KFY72499.1, ECO:0000313|Proteomes:UP000029295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-103 {ECO:0000313|EMBL:KFY72499.1,
RC ECO:0000313|Proteomes:UP000029295};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
CC {ECO:0000256|ARBA:ARBA00008695}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY72499.1}.
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DR EMBL; JPKB01001202; KFY72499.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094E1R6; -.
DR HOGENOM; CLU_004298_1_0_1; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000029295; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051377; F:mannose-ethanolamine phosphotransferase activity; IEA:InterPro.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd16023; GPI_EPT_3; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR002591; Phosphodiest/P_Trfase.
DR InterPro; IPR037675; PIG-O_N.
DR InterPro; IPR039524; PIGO/GPI13.
DR PANTHER; PTHR23071:SF1; GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3; 1.
DR PANTHER; PTHR23071; PHOSPHATIDYLINOSITOL GLYCAN; 1.
DR Pfam; PF01663; Phosphodiest; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 61..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 509..528
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..595
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 607..627
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 639..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 666..685
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 691..709
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 769..787
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 807..829
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 972 AA; 104373 MW; 85EBFFDB06C74F87 CRC64;
MASSSPDYAR IQALYAKARE IKAKEDAAAA IKKEASRLPT AAEKRDAICA ADFRRQWNWT
TLFFTWLFLV NAAGIYFFTK GFLLTRLVLE EHSTCADPPR HYTPDSAREG CWHPRSFEKA
VVVIVDALRY DFAVPVNGSE EQPALACHNA LPFLYETAVK EPHNAFLLPF IADPPTTTLQ
RLKGLTTGTL PTFIDAGSNF AGTAIEEDNL LMQLKVAGRR IAHLGDDTWT ALFPGYFEEK
VSRAYDSFNV WDLHTLDNGV IEHVMPLLKS KPKSAEGVGK EDWDVLIAHF LGVDHAGHRY
GPDHPAMTAK LAQMDDVLRD IVAALDDDTL LVVMGDHGMD AKGDHGGESD DEVQAALWMY
SRRGIFGRTA PETLLPPASA KDARAVNQID LVPTLALLLG LPIPFNNLGR PIEEAFAGRK
GNDWANLASV AAMTAAGVER YQDAYFKARG IEEGNAGTRA LWGGAQEALQ RSLGGEKGTY
KRAYELLTAY QRETLDICRG LWARFDVTSM VQGLAIMAAS LVVLLLFARN AGTDSPVMSP
ELEQAELQLE KNGVDAPANA DADGMDSEPD DFTTSVVKGA FIGILAGASL GVTASSLSPE
PSTVNDTLLG ATACSLLAAL VAALGSPLPY RAPFPTTPWS FLALLLPALP AIGFGANSFT
IWEDQILLFL LTTLGLIFLF ASFSLPSPER TLGITQAVLF TLLTWLASLS KLCREEQMPF
CRSTYYASAT SSTSAPWQLA LPYLTTLLLP SVLKSYLLPS RNYRGPAPLF LNTLRAGLLA
CAIFWTLDAA DDGAWFPFLP TGLLKTARVA IAQVVLGIGF VAGPVAYAYS SPCVSITRAA
TQGPSSTAAP AAASSRMTVT VLGYANAQGK ANGRLRARAR RVADPRAGGT GRCAETPRVA
HCARGSGTDG VLLLFQDWAP GYAGQFAVGE RVCAIACCGV PVEPPDGGVE YFWWPDTCRA
GSIACGAVEE GG
//
