ID A0A094EEY0_9PEZI Unreviewed; 2248 AA.
AC A0A094EEY0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Carrier domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=V499_05002 {ECO:0000313|EMBL:KFY74983.1};
OS Pseudogymnoascus sp. VKM F-103.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420912 {ECO:0000313|EMBL:KFY74983.1, ECO:0000313|Proteomes:UP000029295};
RN [1] {ECO:0000313|EMBL:KFY74983.1, ECO:0000313|Proteomes:UP000029295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-103 {ECO:0000313|EMBL:KFY74983.1,
RC ECO:0000313|Proteomes:UP000029295};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY74983.1}.
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DR EMBL; JPKB01000765; KFY74983.1; -; Genomic_DNA.
DR HOGENOM; CLU_000022_6_0_1; -.
DR Proteomes; UP000029295; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR GO; GO:0009403; P:toxin biosynthetic process; IEA:UniProt.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 3.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR030918; PT_fungal_PKS.
DR InterPro; IPR032088; SAT.
DR InterPro; IPR001031; Thioesterase.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR04532; PT_fungal_PKS; 1.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF00550; PP-binding; 2.
DR Pfam; PF14765; PS-DH; 1.
DR Pfam; PF16073; SAT; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 2.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 2.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 381..813
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1661..1735
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1789..1870
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1743..1790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1746..1781
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2248 AA; 244373 MW; 726372E7E5154B38 CRC64;
MAEKISFLLF GEQSLDTQGF LADFCRNGNP SILSHAFLNR VASTLQNEIE RLPSLERRHI
PSFTTIQELS QRYHTRDVTH PAIDSALLVT TQLAHYIDRA EKVPEDATRP QETWTVGLCT
GLIAAVAVSI APSLSALVNI GAEFVLLAFR TGRHVSALAE HIHESGDAAK SWTYVVPGLN
EPAGRSLLAD FNESKGYTTT SQAYISAITS TSIAFSGPPP TLKALVDEHE FKDGPLPLPI
YGPYHASHLY SAAEIEAVLR LNDSNLSEVL KNASRRFPVI SCSTGQWLAE KDPKKLITAV
IRDILLEPLN FQRVLASCVT QANNYRSSSC LVIPFGPTQA ASSLVQQLKN ETGLEVHLRR
APHSKKDRMA PHTGDHGSSK RCKLAIVGMA GRFPDAATHE KLWELLEKGL ALHREVPADR
FDMKTHCDPS GKVMNTSHTS YGAWIENPGL FDPRFFNMSP REAHQTDPMQ RMAITTAYEA
LEMSGYVPNR TRSTKLDRVG TFYGQTSDDW REINAAQEVD TYFITGGVRA FGPGRINYHF
GFSGPSFSID TACSSSMAAM QLACTSLWAK DCDTAVVGGL SCMTNSDIFA GLSRGQFLSK
NGPCATFDND ADGYCRADAC ATVIVKRLED AIADKDNVLG VILGTATNHS ADAVSITHPH
AGTQEILYRN ILNMAGVDPL DVDYVEMHGT GTQAGDATEM KSVTNVFAPA DQKRSAEQSL
YLGSVKANVG HGEAASGVTA LIKVLMMLQK NTVPPHVGIK KTINRTFPKD LAERNVHIAY
HSTPLLKKAG QPRRVFVNNF SAAGGNSGLL LEDGPATKTL LTDNRSAHMV SITAKSKSAV
IKNAERLMYY IEQHPEASLA DISYTTTARR IQHNWRISVT GFNITQVREF IKHKLTEDIT
PIPLTTQEIV FVFTGQGSHY AALGKELFES SSLFKETMLE FNNIAAMYCL PSFLPLIDGS
AAAVEDLSPV VVQLGLLCFE MAMARLWASW GINPSVVIGH SLGEYAALNV AGIISASDAI
YLIGKRAQLL MEKCTVSSHG LLAVKASVLS IRESVDEASI NIACINGPEE TVLSGDTALI
YVISERLTAA GFKCMQLKVP FAFHSAQVDP ILDKFEKLAA SVQFHAPTAP IVSTLLGRQL
REGETVNASY LRRHAREPVN FLDGINSIRS AGLVNEKTLF LEVGPHPVCI GMVKSTLGKE
TVAVSSLRRT ESAYKTLSDS LSTLHTAGFN IDWNEYHRDH LECVQLLDLP TYAFDEKNYW
IQYTGDWCLT KGRASDSQVA SCQDSKPKIS TTTVHKVVED LVDGDVATVS TESDLARADL
RSAVMGHLVN GAGLCPSSIY ADMAMTVCEY GYKLVRPDVE NIGINVASME VIKPLIARPD
GASQILKLTA YIDASRSSAK LIFSSGSDKA RVDHAHCVVS FGDCAAWLSE WERVAYLIQH
RVDWLKNAEK NGKASKIGRG LAYKLFSALV DYDAKYRGME EVILCSENME ATSHISFQTK
PTDGTFVCSP YWIDSVAHIS GFIVNGSDAV DSGNQVYVSH GWDSLRIAEP FSAEKTYRSY
VKMQPAGGKM LAGDVYVFDG SRIVAVVGGL KFQCILRTVL NTLLPPVGVT APPAQAPVAE
PSPAVAIPTT STLHKTTTTT TKIKTAQDST TSLEPASKKF VTICSQTMDI VAKEVGVGMD
ELVDNITFAD LGVDSLMSLT IGGTVREKLE IELPSSIFLE CPTIGQFKSF LARFERADSE
ISEDTEDSIL YTNTDDSTPN TDDSTPNSDS STPNFGEMSP LSTPADDSDL ELSKDDQLCE
IIQNTIAVEV GVTTQEVAHA LDLALLGVDS LMALLILGKL REKTDLSLPA DLFVTCASIK
DIERKLGIGQ PPKPVRIPAR SFPKLLPRPI STETVSPKET GHQVTNITPE RFATSVLLQG
KIRTATSHLW MVPDGSGSAT SYADIPEISP GLAMWGLNSP YMKTSEEFTC GVPGIAAKYI
QEVKRRQPVG PYLLAGWSAG GVIAFEMLNQ LVKAGDRVSH LIMIDAPCPL IIEALPTSLH
RWFASIGLLG DGDPNKLPSW LLPHFAASVA ALSTYDAVSI PKDKAPSVTA IWCEDGVCKN
ESDPRPDPYP EGHALFLLDN RSDFGPNLWD SLLPAEKIRC VPMKDALLKR ASKVLLITMY
DHYLDSRFDY VTQSKLSHPS VTILARDALP VLETHGQKRA LSDIINDLNT KKSYGRSGLS
QAASAQLHVE DVAALSDSAI GRRTGTEP
//
