ID A0A094EUQ2_9PEZI Unreviewed; 577 AA.
AC A0A094EUQ2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN ORFNames=V500_10515 {ECO:0000313|EMBL:KFY82481.1};
OS Pseudogymnoascus sp. VKM F-4518 (FW-2643).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420913 {ECO:0000313|EMBL:KFY82481.1, ECO:0000313|Proteomes:UP000029284};
RN [1] {ECO:0000313|EMBL:KFY82481.1, ECO:0000313|Proteomes:UP000029284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4518 (FW-2643) {ECO:0000313|Proteomes:UP000029284};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY82481.1}.
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DR EMBL; JPKC01003494; KFY82481.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094EUQ2; -.
DR STRING; 1420913.A0A094EUQ2; -.
DR HOGENOM; CLU_025218_3_0_1; -.
DR Proteomes; UP000029284; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04396; RhoGAP_fSAC7_BAG7; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR PANTHER; PTHR15228:SF25; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029284}.
FT DOMAIN 84..284
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 473..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..380
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..502
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..525
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 62302 MW; 8A22F54918999E35 CRC64;
MSSGHSAQSG QQQYSQPQPK TLRHFPLAHQ SAPAPPAASP PTKRDLKSWW KGFKSQRNQE
TQEQPAGIFG VPLRQSITYA NVAISLVDAE GNSYIYGYVP IVVAKCGVYL KEKATNVEGI
FRMSGSEKRI KELRALFDAP DRYGKGLDWD GYTVHDAANV LRRYLNQLPE PIVPLDLYDR
FRAPLRSVMG QEVVSPEDTN GIIQTYQQLI TELPPLNRQL LLYILDLLAV FSSKSDENRM
DSANLAAIFQ PGMLSHPQHD MAPEEYHLNQ NVLVFLIENQ DHFLIGMRGT AADEKTVQDV
QKGGTPPPAT PTSITKKSGI SRSLSNASAG GDNPRHTGGV RRNVSVNSGH SRRSNGAPAS
PGLRPLTQTP AENGGNGTTS IKEVRNAECT GLMILVLPHD GSLKGGAALR PNTAKLGYVP
LPQTALPSEQ RRLLDHSGGV VWDNGNNENK GAVWTISTEE VKFQQVVAGQ RPYGSSCRAA
SPSQHELLLS PSPPPPPPPL DNLDKQTETR SGAAVGTSPT PSSRAPSPCA LGLPAATAQS
TGSGLCINRA SARLVLRGED GDGFVDWCSR PFCEWVG
//
