ID   A0A094G6X3_9PEZI        Unreviewed;       682 AA.
AC   A0A094G6X3;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN   ORFNames=V497_00279 {ECO:0000313|EMBL:KFY67602.1};
OS   Pseudogymnoascus sp. VKM F-4516 (FW-969).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420910 {ECO:0000313|EMBL:KFY67602.1, ECO:0000313|Proteomes:UP000029268};
RN   [1] {ECO:0000313|EMBL:KFY67602.1, ECO:0000313|Proteomes:UP000029268}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-4516 (FW-969) {ECO:0000313|Proteomes:UP000029268};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY67602.1}.
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DR   EMBL; JPJZ01000040; KFY67602.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094G6X3; -.
DR   STRING; 1420910.A0A094G6X3; -.
DR   HOGENOM; CLU_403392_0_0_1; -.
DR   OrthoDB; 1790722at2759; -.
DR   Proteomes; UP000029268; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd05195; enoyl_red; 1.
DR   Gene3D; 3.30.428.10; HIT-like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036265; HIT-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR013968; PKS_KR.
DR   PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   Pfam; PF08659; KR; 2.
DR   SMART; SM00829; PKS_ER; 1.
DR   SMART; SM00822; PKS_KR; 1.
DR   SUPFAM; SSF54197; HIT-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000029268}.
FT   DOMAIN          3..165
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
FT   REGION          463..506
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        474..491
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   682 AA;  75126 MW;  301ACBC62255CA9A CRC64;
     MAELIGTATF KGVISLYKLI QSFRHHPKHR TSIFNSRDKT FRRDLMRETS NRGVDVVLNS
     LSGELLHKSW KCVAEHGKMI EIGKRDFVGG AQLSMNLFEA NRTFIGVDLA RFTPEMYQPL
     MAKVIDMYQN GLIRPIAVSR IFDASEVEGA FRYMQKGSHI GKIELRLDAS YLLVDGLGGI
     GRQVSTRMVE HGARHLIFLS RSAGESAEDQ ALLHELKIQG CYAQTIAGSV ENPQVVGKQD
     RTFDAMTYED WTLAVGAKVT GTWNLHNASK KCNLDFFVLF ASLSGALGSP GQANYAAANT
     FLDAFVQYRH QQGLPASATD LGLMGEMGFV KEGLTTVDNE QSRQFLTNAI GVQIYQFMTQ
     PVEDVNPSTS LKSLGVDSLI TIEASLRDKL VRVNATAHGA VTDIYLRSKL ATGEVGLIQP
     EVHMSSFRSC RTALHAPRSG AFALRQPAVN YQTLSPLRML YKDDQDPKSL KPKSTEGSKS
     STDQGAAETD TAFDPSRTHP EEEKNAADNK LALQHALAAL AGAYQANGQV KNAVELLEQV
     CAVLGFWLPI VSRGIMGGLL GSNWESKGMS WNVVQANGVQ AGQNIKHAHF HIIPRPRPEM
     LSLYSTTRDV STLMDYDRRA AAVAEGLRTR LADEEGLEAC MMIKTALRKE ITRLKVEGKI
     VEGDKEWELW SVTEVGGRGM RL
//