ID A0A094GJF7_9PEZI Unreviewed; 856 AA.
AC A0A094GJF7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=CNNM transmembrane domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=V502_11154 {ECO:0000313|EMBL:KFZ03195.1};
OS Pseudogymnoascus sp. VKM F-4520 (FW-2644).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420915 {ECO:0000313|EMBL:KFZ03195.1, ECO:0000313|Proteomes:UP000029308};
RN [1] {ECO:0000313|EMBL:KFZ03195.1, ECO:0000313|Proteomes:UP000029308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4520 (FW-2644) {ECO:0000313|Proteomes:UP000029308};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ03195.1}.
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DR EMBL; JPKE01004253; KFZ03195.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094GJF7; -.
DR STRING; 1420915.A0A094GJF7; -.
DR HOGENOM; CLU_011310_3_0_1; -.
DR OrthoDB; 248389at2759; -.
DR Proteomes; UP000029308; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR PANTHER; PTHR12064:SF100; PROTEIN MAM3; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000029308};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 154..335
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 354..416
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 420..481
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 643..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 695..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 758..788
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..803
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..833
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 856 AA; 92730 MW; C8E1199E81D38BA8 CRC64;
MPSSRPKSPP YWVAKHSNPA PLLQFYPYSA LHYYATILLE YTLLYCAKAL WTKLPNLAFG
VSAVNCMLPA LNRYFVEGKR AKPAIDRTLL KPLASTMTIR SHNSRYNASP GGTRPAVVGL
AKVLFLAASQ MSLAGAAPLT SWIKGHEDLP KSPDDPDLWL YLTVAMVLVI SGGAFAGLTI
ALMGQDGIYL QVIATSGEGK EQKHAQRVFK LLKRGKHWVL VTLLLANVIV NETLPIVLDR
SLGGGWPAVL GIIFGEVIPQ SICVRYGLQI GSVMAPFVLV LMYLLAPIAW PTAKLLDYLL
GEDHGTVYKK SGLKTLVTLH KTLGSTPSDR LNQDEVTIIS AVLDLKDKAV GDIMTPMGDV
FTMSVDTILD EETMDAILSA GYSRIPIYEP GNENNFIGML LVKMLITYDP EDCKKVGEFA
LATLPETSPE TSCLDIVNFF QEGKSHMVLV SEYPGEDHGA IGVVTLEDVI EELIGEEIID
ESDVYIDVHK AIRRLAPAPT FRRAAKGQIV ADNDIPKLQG LQGSPVFASD EDYKDGNSGR
RQLSLDAKAP GQSPVTFGTS PKATFMIRRS SAAADGGSVT VRGNATDMRE HLKHLGPSNL
ASRPKTTRYN TVKIKPGVVK DAKDHRTSVH EDHVVFQDDS EMYSAPYGGE GEGLLQSAGR
PASDGVLALQ QGYGSMDHGS SRRTSSPLRV HKFQHVDTNG LDKSQSTKGH PSKGSVTSPQ
SPPRRPELHE SDSGSGGTIS SLRSGHASPA PRKRGTARSG SITENIVDSN GVRKVVLQTT
SSSDGDDTII HSQDGEDGAR NRRETNVNVQ LVEPRPDEEA PSDGQAEVDD VKKKTKRRRK
RKNHKDSEGG GPSQDA
//
