ID A0A094GL03_9PEZI Unreviewed; 899 AA.
AC A0A094GL03;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=V498_02499 {ECO:0000313|EMBL:KFY96755.1};
OS Pseudogymnoascus sp. VKM F-4517 (FW-2822).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420911 {ECO:0000313|EMBL:KFY96755.1, ECO:0000313|Proteomes:UP000029270};
RN [1] {ECO:0000313|EMBL:KFY96755.1, ECO:0000313|Proteomes:UP000029270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4517 (FW-2822) {ECO:0000313|Proteomes:UP000029270};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY96755.1}.
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DR EMBL; JPKA01000387; KFY96755.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094GL03; -.
DR HOGENOM; CLU_002458_2_1_1; -.
DR Proteomes; UP000029270; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018:SF26; DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G10920)-RELATED; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 544..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 585..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 610..635
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 685..706
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..176
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 199..392
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 404..676
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 794..891
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 99254 MW; 8CA3C4552A851EF2 CRC64;
MDGLFRRADP APTDSDKDTS VSGLVATLVP TLVVALIYVS IFLILRRSHR RFYAPRTYLG
TLRDNERSPE LPTGMFNWFG TFWKIPDTYV LQTQSLDSYL FLRYMRILVA ICFFGCIITW
PVLFSVNATG GNGAQGLNML AFGNLNKNTD GKYRMYAHVF IGWIFFGFVQ LMVCRESIFY
INLRQAFLLS PVYANRISSR TVLFTSVPNI YLEEAKLRKV FGDEVQHVWI TRDTETLDKL
VEERDKTAFR LEGAETKLIK LANKERLKAL KKGAANDEEP VIATADSESG SIAARWLPAK
KRPTHRTGLL GLFGSKVDSI NWCREKLEKL IPDTEVAREA YKAGADKPVN AVFIEFRTQS
AAQSAYQSLS HHQALHMSPR YIGMHPNEIV WSSLRISWWQ KVVRRYAVQA FIAALIIFWA
IPVAAVGLIS NVPQLATLSW LSWLNDIPDV IMGVVSGLLP SVMLSILMSL VPIIMRILAK
ASGEPTLARV ELFTQNAYFA FQVIQVFLVV TIGSAASSVA KQIADNPSSA ASLLAQKIPL
ASNFYISYFI LQGLTIASGV VSQVVGFFIF GLLYKYLTST PRSMYAKWTT LSALSWGSIL
PVYSNIAVIA ITYSLIAPLV LGFATVGITL FYLAYRYNIL FVTDNTIDTK GLIYPRALQH
LLTGVYLAEV CMIGLFGISA AIGPIILMVV ALVGTVLFHI AMNSALDPLL YNLPKSLEAE
EEVLALESGD YNNGTTAGVP AAAATSNGEK SLEAAGAPAA SADPALLASE ATGEKTVAAL
PAAPHPKPNL LTKFLKPHIY ADYATLRRLV PQDRSGATTT YSPEVERNAY MPPSVRSETP
LLWIPRDEMG ISRQEIAHTA KVIPITDEGA ALDEKGAVYW VAEKEEGARP PIWEEKTYY
//
