ID A0A094H706_9PEZI Unreviewed; 882 AA.
AC A0A094H706;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 40.
DE RecName: Full=Origin recognition complex subunit 4 {ECO:0000256|ARBA:ARBA00019083};
GN ORFNames=V502_08940 {ECO:0000313|EMBL:KFZ09109.1};
OS Pseudogymnoascus sp. VKM F-4520 (FW-2644).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420915 {ECO:0000313|EMBL:KFZ09109.1, ECO:0000313|Proteomes:UP000029308};
RN [1] {ECO:0000313|EMBL:KFZ09109.1, ECO:0000313|Proteomes:UP000029308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4520 (FW-2644) {ECO:0000313|Proteomes:UP000029308};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ORC4 family.
CC {ECO:0000256|ARBA:ARBA00005334}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ09109.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JPKE01002982; KFZ09109.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094H706; -.
DR STRING; 1420915.A0A094H706; -.
DR HOGENOM; CLU_007115_1_2_1; -.
DR OrthoDB; 230201at2759; -.
DR Proteomes; UP000029308; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000808; C:origin recognition complex; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd15492; PHD_BRPF_JADE_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR017956; AT_hook_DNA-bd_motif.
DR InterPro; IPR016527; ORC4.
DR InterPro; IPR032705; ORC4_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12087; ORIGIN RECOGNITION COMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR12087:SF0; ORIGIN RECOGNITION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF02178; AT_hook; 3.
DR Pfam; PF14629; ORC4_C; 1.
DR Pfam; PF13831; PHD_2; 1.
DR PRINTS; PR00929; ATHOOK.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00384; AT_hook; 3.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000029308};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 342..392
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 28..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..238
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 882 AA; 97124 MW; 1D5E35EE20DE11F5 CRC64;
MDRAGMYPLT PISVTRLSAT IKFRVSLPEG SQSARANSSM PILPDMQPPD CRPLDQQVND
SSPMPSSGRL SAKRRKVGGS GSSPSTPNAV EAVKRTSRRS LNAVLLKENE PIDDDSHREP
SPTEQILEDE AAAESMSPKP TNEAAAEAIP GSEPASRSAG RQKRKPRRYS TEVANTEVAE
RLVLEPKSIL TPSKRERSRP RKSVAFEQTT PAGGEVDLGF KDIPIDHPPP PVQTPTPRKR
GRPPKNNDLQ ELSQPEKVVT ADVAEETGPR NTRDLQDLPQ PENAVTADVS EETVPPKRGR
GRPRKIRDPQ ELSQPEKVTK SPKSNPRIPI ILEPDEEEEE DEEVCAICEN GDSEAPNEIM
FCDSCDLAVH QECYNITTIP EGEWLCSDCQ PEDPAEDTAD AQQAVSEIPS ESIFDIGGSE
PPAILGLEDH LMTMQRLLLD KLTGRKRLKL HDLDDEFQKV YQVVEQTVMS GEGNSMLVIG
ARGSGKTTLV ETVISDLSIE HRENFHVVRL NGFTHTDDKL ALRDIWRQLG REMEVEEDLT
AKTNNYADTL TSLLALLSHP TELSEDRANH MAKSVVFILD EFELFASHPR QTLLYNLFDI
AQARKAPIAV LGVTTKIDVV ETLEKRVKSR FSHRYVHLPL PRSLPAFWEI CKEGLQADMD
ELVDAGFDPG VPGQEEFLEY WDTMINSLYN DDAPYKAHLQ RIFYRSKSVP AFFSTCILPI
ASLTPRSLPL TSASFPAHST LSPPDSKLHI LQGLSDLDLA LLICAARLDV VLDTDTCNFA
MAYDEYSTLT ARQRIQASST GIGALSASYK VWGREAAMGS WETLVDYELL VPASMGAGPM
GGLGGGGVGR EGKMWKVDVG LEEIAGSVGG LTSVMTKWCK EI
//
