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Database: UniProt
Entry: A0A094IUX6_9GAMM
LinkDB: A0A094IUX6_9GAMM
Original site: A0A094IUX6_9GAMM 
ID   A0A094IUX6_9GAMM        Unreviewed;       466 AA.
AC   A0A094IUX6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   25-OCT-2017, entry version 26.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:KFZ30912.1};
GN   ORFNames=IDSA_07500 {ECO:0000313|EMBL:KFZ30912.1};
OS   Idiomarina salinarum.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Idiomarinaceae; Idiomarina.
OX   NCBI_TaxID=435908 {ECO:0000313|EMBL:KFZ30912.1, ECO:0000313|Proteomes:UP000054363};
RN   [1] {ECO:0000313|EMBL:KFZ30912.1, ECO:0000313|Proteomes:UP000054363}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ISL-52 {ECO:0000313|EMBL:KFZ30912.1,
RC   ECO:0000313|Proteomes:UP000054363};
RA   Du J., Shao Z.;
RT   "The draft genome sequence of Idiomarina salinarum ISL-52.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KFZ30912.1}.
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DR   EMBL; JPER01000003; KFZ30912.1; -; Genomic_DNA.
DR   RefSeq; WP_034775449.1; NZ_JPER01000003.1.
DR   EnsemblBacteria; KFZ30912; KFZ30912; IDSA_07500.
DR   Proteomes; UP000054363; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054363};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054363}.
FT   DOMAIN      163    294       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      374    443       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     171    178       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   466 AA;  52869 MW;  E36CBFE068A373B5 CRC64;
     MNKSLWQYCS ERLQSELSTQ HFNTWIRPLQ ADMSDDTLTL YAPNSYVVDW VKDKYLNLIN
     DYLGELVKEK GGRAPNVAFT VGGMQAPSGN GSSRPAPAQQ QRPVNRLNGA IRRQNPWDRD
     ETPAPAFECN IHPEYTFDNF VEGKSNQLAR AAALQVAENP GGVYNPLFVY GGTGLGKTHL
     LHAVGNAIMG HKKDAKVFYM RAERFVQDMV NAIKNNSINE FKRYYRSVDA LLIDDIHFFA
     NKKGSQEEFF HTFNALLEGN QQIIMTSDLY PKEIEGVEDR LRSRFGWGLT IAIEPPELET
     RVAILIRKAQ ERGITLPHEV AFFIAKRLRS NVRELEGALN RLAANVNLTG RQITIDFVRE
     ALRDLIAAQE KLVTIDNIQK TVAEYYNIKM ADLLSKRRSR SVARPRQLAM ALSKELTNHS
     LPEIGDAFGG RDHTTVLHAC RKIQELKDAQ HDIKEDYRNL IRTLSA
//
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