ID   A0A094IYG3_9PEZI        Unreviewed;      1190 AA.
AC   A0A094IYG3;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=MaoC-like domain-containing protein {ECO:0000259|Pfam:PF01575};
GN   ORFNames=V502_00287 {ECO:0000313|EMBL:KFZ25236.1};
OS   Pseudogymnoascus sp. VKM F-4520 (FW-2644).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420915 {ECO:0000313|EMBL:KFZ25236.1, ECO:0000313|Proteomes:UP000029308};
RN   [1] {ECO:0000313|EMBL:KFZ25236.1, ECO:0000313|Proteomes:UP000029308}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-4520 (FW-2644) {ECO:0000313|Proteomes:UP000029308};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971,
CC         ECO:0000256|PIRSR:PIRSR602403-1};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFZ25236.1}.
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DR   EMBL; JPKE01000109; KFZ25236.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094IYG3; -.
DR   STRING; 1420915.A0A094IYG3; -.
DR   HOGENOM; CLU_271916_0_0_1; -.
DR   OrthoDB; 1611592at2759; -.
DR   Proteomes; UP000029308; Unassembled WGS sequence.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   CDD; cd00302; cytochrome_P450; 1.
DR   CDD; cd03448; HDE_HSD; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR002403; Cyt_P450_E_grp-IV.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR002539; MaoC-like_dom.
DR   PANTHER; PTHR42877; -; 1.
DR   PANTHER; PTHR42877:SF7; FLAVIN-BINDING MONOOXYGENASE-RELATED; 1.
DR   Pfam; PF01575; MaoC_dehydratas; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00465; EP450IV.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|PIRSR:PIRSR602403-1};
KW   Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR602403-1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|PIRSR:PIRSR602403-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029308}.
FT   DOMAIN          719..830
FT                   /note="MaoC-like"
FT                   /evidence="ECO:0000259|Pfam:PF01575"
FT   BINDING         494
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602403-1"
SQ   SEQUENCE   1190 AA;  134045 MW;  F6601C83E346AB99 CRC64;
     MTVNRTRQFY LVGVTPPATR EVDVDSILDL KTLKTNLGLA FHIIEPASID FQTDEHGAIE
     GLEGILDATA PIGITINGQP VREVLGPKGL PGVGPYYEIF PDHLGNIIRL LRKYGSVVKA
     VNMGKVNYHT DDPVIAGYLF SESIYFTKKI TPNHPLWGIK DNTAIFIGDT EIKAWQQNHK
     FLPPSLSPKA IRHYTPLMEQ TVRGSFKVFD AIDAAGETLN VYQYMHKLAA QTIGKFCLGL
     DFGHFNEPDS PVDPIIHDIA DMLLLNKKVT ARGDWYGALP FGDPKRLKDM QQRTYSRLQG
     AMDTVDSRDK PDLPMADAAL KATCVVDYLN RAIDENGQKL PKDLILPNMV IMTAAGFTTT
     SALLSWMIYS AITYPGEQER LLQELIDSNI NNDISWTPEY AANLKYLDKF VKETQRLHNP
     SFQPARTTKT DVILPGGWHL PADAVLVPAL YAIHTNPAVW ENPLRFDVAR WDTEAVKKRH
     RCAYVPFAAG PRGCIGFNFA LQEVKILFSE LLYRYEFSKE SHGAVDYDPD FQLIRPMNLS
     SSYYRTTKNG LTCEAAWCRI QVPQCSLLME RARLPPFFRQ HWLQSPRELH PDFQPFPTYP
     VILQFKGSYQ SIIDYYTTTR TPAIPGVPPV DQTRVLDGQR HIQIFQPLPA SSTGHAFELQ
     ITCLGVADKG PAGMITETEA LLVDTLTGTT YCRILRQSFA VGQGGWGGPK KQKETVYVTP
     KREPDAVYTQ VTTKETAHLY RLNGDYNPLH CDDEVAKKAG FKGIILHGLC TWNMSAHAVL
     STFAGGDGRR LREFQARFKK VVYPGDTLLV EMWRMGRKNG LEEVLFRTSV EGQEVLNNGR
     ALLAVESVGT KLPTWITAGF GQKFAGPNGA NFQYTDEQKA EWARDPEKYR EYRKMIELEL
     NQRFKLVLRN TEESDEANEF SYKEMCIKLS NNPRLIDNII PKNFNVSCRR PTPGNGFLDC
     LVGEKTTCYT DTIGGITPNG FLTADGTEVE VDVIICATGF DTSFRPQFPV IGLDGKSISE
     KWAGLPLSYA AVGVPNVPNY FMYSGPFSPV AQGSVLPLLT LGTKHFLQVI RKMRKEHIRR
     LSPKEGPTRD FGEHAAMYLK RTAWVDPCSS WFKQGTTDGP LVMWPGSRLA FFDHMAEPKY
     EDYEIEYVSG NRWGYLGNGF TREEFSPEDD VTFYLDDKYL RDHVQKNKES
//