ID A0A094JTM8_9PEZI Unreviewed; 2740 AA.
AC A0A094JTM8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN ORFNames=V501_04238 {ECO:0000313|EMBL:KFZ12448.1};
OS Pseudogymnoascus sp. VKM F-4519 (FW-2642).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420914 {ECO:0000313|EMBL:KFZ12448.1, ECO:0000313|Proteomes:UP000029315};
RN [1] {ECO:0000313|EMBL:KFZ12448.1, ECO:0000313|Proteomes:UP000029315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4519 (FW-2642) {ECO:0000313|Proteomes:UP000029315};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ12448.1}.
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DR EMBL; JPKD01001388; KFZ12448.1; -; Genomic_DNA.
DR STRING; 1420914.A0A094JTM8; -.
DR HOGENOM; CLU_000637_1_0_1; -.
DR Proteomes; UP000029315; Unassembled WGS sequence.
DR GO; GO:0005643; C:nuclear pore; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR021827; Nup186/Nup192/Nup205.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR Pfam; PF11894; Nup192; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000029315}.
FT DOMAIN 2126..2380
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 564..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1680..1704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2740 AA; 305828 MW; 00FA03651E2A6AD4 CRC64;
MAELTDLEGL ELLHRDLVAQ AEQRLPNIDR LWVQLETRLD EFRRLLDKAP RNEQSRKSLD
SGRIQIQDEE YSINDDFKQG ALMLADAVNL DELDAARIFF ASQEDADVLG RSVLECSIIR
FHQTRKYLLD CFRLVLQLSS ANTDSDSDSN SDELEVQENI KSTFQTAVGL VLQTDNKAEN
GPSFVKKCLQ SMADIKTWLQ DLADRVNSAN VLYQGQTDEF SETIEYQRVS LIQQHESLGS
IVHCLVKARY SSVENFETVL GVLRQTDRFD NLLVHYFPAT AAFISTFGSP EGSGSLQQAR
SLNRMILENK DKNNWTLQYV YAGVSVLWLG EYSGWYLDNQ GNSPAVGVNL DDEKRTRSEQ
FAGFLKDGAF EFLLSLGADV KSGDWQDPAR QGLRRWLQNK VPPMLQDSVP FSEFFQLALK
EQLEAFIDAF ITNMPDPLRK LRTEEQEQRQ LSLTYEHDLD LERFLVIISY AFEQRPDAAL
AFWSDPDSNL AGFLQWASCR ASTPLLSAFC EMLQAISEDD ECATASHRFL LEESTTASGK
LRRSQSLTWS QIFTDLTHYT SKLRNQPAPH QSTSYRAGKP GANEVESEPE ETLMLESYLR
LITRLCTGSE EARTFILKHP SFHLTGLLYE LASSRIESRL RACAFTTLRS LLSQKSKEIN
DITWMSLDQW ISGGHSTMPK VSLTMSTSAS ITSGIFEEIS TGFEEPNSFI QFLTALLTPA
EPSMGLNDDL PFPENLGSSK RMPGIDTYID FVVGQIFVRK SRTAEIISQP QQRLLSLTCL
DFISTCLSTF NEDLVVFANQ SNVSVDSAIR ASDLDTYVRL HPFSRTMEWM FNEKVMDALF
QSVHEEISAV GNAAPSSPLV LSILAAIHVI TLIMDLQPTY LDIIRPLNRQ QATHARPPVA
NAAYASFDDG VLSHLSVIVD LGLYCGSGHS ELAVASLKLL QRFSTSPKLI SPPVSNIGGR
RDRNKAIAAL EMGNDSERIA RSLISEFESN IDMEEASESP AYNIKIHILD FVNACLQAMP
NRPSIAHLLL GFRCESESLE VLPDSPFARD ASLFHSIMKL AIQCPVQTEQ NVIAPWLTRL
KSKALQVMRT LWRSPISSQV VMVELRSHNF FTHLWTSEVI IGPQTISGLG LPNETYFGVI
ESQNDINDYL SQRSMLFQYV ASELRRVSKD GSTSVRQQIS NTLLGRTTIE DGTEIQNYTI
FDMFDFMVVD PAAETFPISP YFKDLNFSVC LTGNPGEPHV YDVKRVEALL VLRQSEMKVA
GYLQKPEDEA IFVAEALNLL RYLASQSNIS RLHATWLETL EGWTQVVLMT VTVGDLEDTN
KLRAILEAVL VVQSKLERHS SVNIEASQKL ATLAKFLLFN IDFTSEPFRN DDVASLANER
LSQLFSVSLK AIQSPISDSH FRETLYTICY KYLVGMSDMP RGLTTGRQYI TQTIKSSGES
LVAIICDDAY AGENTCRISA LLLLGQIVEL ARKEDSSYIN TTLSRINFIG LLVDSLQNIL
DEMQDLRTDE IDMYLLYVNA KLALLVQVSQ TRSGATAVLG AGLFQIIRDS GVFSTDPDIG
LDIADIDAIK KHYGLLLALM RVINCCVVSR GPQNEQTLAQ AKKFVSENRL WMLSVFKRSA
RIGAAVNNEL DEVVDELSDA YMLLISMSGF LDMRPSEGNS TDSTSDRPVP AKRRIADTLG
TGVATAASMP GGDKPGSRSE AKRQRTIEST IAGHPKGKMS ETIGLVAPSN VDFRRTVGFQ
PQSGVRKLVV KNLRPSRVAD LREHYGKVQV QVLDAVTAIL KDQQPRQPLE RLYRDVEDIC
RNNQAEGLYK ELRHRTSDYL ASSVLGSLQK ADNGNDPLQF LEALLDAWKD WNAKAMRIRA
VFGFLDRSFL LNSKEYPQLN DMSIQQFRSV ILENPAIDGQ VYDATNKMID NDRKHGGQDS
ARWFKSTLFK DIIMMLLITN LYKARFEPKF LEYSRQFFSE FALIDADLKN MISQCVKLLE
KEGARCDIHN LDSGTKRELL SDAQDILIRD RSEFLLDVHA VGSLLEARAI ESLKSLYGLL
KGSEIQDKLK TPWEEYIKRA GATIVSDQGK GDDMVVRLLE LKRSLDLITR DAFNKDEIFK
FSMREAYSTF INDRKSATVW GTGNSKVGEV IAKYIDLLLR GGLKAVPRSL ASDELDRMDA
EKQGLASTGD EDAELDRQLE QGLELFRFIE GKDVFEAFYK KDLARRLLMA RSASQDAERN
MLTKLKSECG SNFTHNLEQM FKDQELSRDE MISYKQSLSN TSKTTMDLQV SVLSAAAWPT
YPDIAINLPA EVARHIEKFD RHYKNKHTGR RLTWKHSLAH SIVKGHFKKG VKELQVSGFQ
AVILVLFNDL ADDEALSYTA LQASTGLIDA ELTRTMQSLA CGKVRILTKH PKGREVAKTD
TFTVNLAFTD PKFRIKINQI QLKETTAENK ETHERVALDR QYETQAAIVR IMKSRKVLPH
QSLVAEVIEQ TKMRGAVEVG EIKKNIEKLI EKDYIERDEG NYTPNPRLRS ALRRWEVAAR
LAASDSGAGE REVRATTIST KDVVVVCAGG NSAPNVLECD ARDIDAVGGN TSWATVEIVL
LHVDAVPVDV PKRDAAVGGI YNDWGAYSAV GAGVGLDAAS VLAVGDDRVG ERNTVDDVVT
LASNGTDAQS VAANAGHTRN EDVTTASHSD AVILVVDDRV FERQAAGGGY VEAVRVVGGS
QTVADGVRRV SGSVVQIDVV KGEAAAARDG EAVDRPVPDV
//
