ID A0A094KBB4_ANTCR Unreviewed; 564 AA.
AC A0A094KBB4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 03-MAY-2023, entry version 51.
DE SubName: Full=FYVE, RhoGEF and PH domain-containing protein 4 {ECO:0000313|EMBL:KFZ55458.1};
DE Flags: Fragment;
GN ORFNames=N321_04438 {ECO:0000313|EMBL:KFZ55458.1};
OS Antrostomus carolinensis (Chuck-will's-widow) (Caprimulgus carolinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Caprimulgiformes;
OC Caprimulgidae; Antrostomus.
OX NCBI_TaxID=279965 {ECO:0000313|EMBL:KFZ55458.1, ECO:0000313|Proteomes:UP000053620};
RN [1] {ECO:0000313|EMBL:KFZ55458.1, ECO:0000313|Proteomes:UP000053620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N321 {ECO:0000313|EMBL:KFZ55458.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR EMBL; KL345369; KFZ55458.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094KBB4; -.
DR Proteomes; UP000053620; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd15741; FYVE_FGD1_2_4; 1.
DR CDD; cd15791; PH1_FDG4; 1.
DR CDD; cd13236; PH2_FGD1-4; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR037742; FDG4_N_PH.
DR InterPro; IPR035941; FGD1-4_PH2.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12673; FACIOGENITAL DYSPLASIA PROTEIN; 1.
DR PANTHER; PTHR12673:SF98; FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF00169; PH; 2.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00233; PH; 2.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 2.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053620};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 7..194
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 223..322
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 361..417
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 362..412
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 445..542
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFZ55458.1"
FT NON_TER 564
FT /evidence="ECO:0000313|EMBL:KFZ55458.1"
SQ SEQUENCE 564 AA; 65278 MW; 57687A4932D04588 CRC64;
QETDEQKRHK IASELLQTEK AYVSRLDLLD GVFYSRLLEE ANRGSFPAEV INKIFSNISS
INAFHSKFLL PELEKRMQEW TTTPRIGDIL QKLAPFLKMY GEYVKNFDNA MELVKTWTER
SPQFKFIIQD IQKEKVCGNL TLQHHMLEPV QRIPRYEMLL KDYLRKLPQD SLDWKDAEKS
LEIISTAASH SNSAIRKMEN LKKLLEIYEM LGEEEDIVNP SNELIKEGQI LKLAARNTSA
QERYLFLFNN MLLYCVPKFS LVGSKFSVRT RVGIDGMKII ETHNEEYPHT FQVSGKERTL
ELQASSEQDK EEWIKALQNT IEAFQQRNET FRNAIAKEYE DMPVEVSNAE LGKRAPRWIR
DNEVTMCMKC KEPFNALTRR RHHCRACGHV VCWKCSDYKA HLEYDGNKLN KVCKDCYHVI
IGCTDSEEKK RKGILEIESA EVSGNSVICS FLQYMEKSKP WQKAWCVIPK QEALVLYMYG
APQDVKALAT IPLLGYTVDD TPRSADLPHS FKLTQSKSVH SFAADNEELK QKWLKVIHLA
VKGETPECQV NLEEQPEPSK TTEC
//
