ID A0A094KDY5_9PEZI Unreviewed; 1470 AA.
AC A0A094KDY5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=chitinase {ECO:0000256|ARBA:ARBA00012729};
DE EC=3.2.1.14 {ECO:0000256|ARBA:ARBA00012729};
GN ORFNames=V501_00455 {ECO:0000313|EMBL:KFZ19838.1};
OS Pseudogymnoascus sp. VKM F-4519 (FW-2642).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420914 {ECO:0000313|EMBL:KFZ19838.1, ECO:0000313|Proteomes:UP000029315};
RN [1] {ECO:0000313|EMBL:KFZ19838.1, ECO:0000313|Proteomes:UP000029315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4519 (FW-2642) {ECO:0000313|Proteomes:UP000029315};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00000822};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC class V subfamily. {ECO:0000256|ARBA:ARBA00008682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ19838.1}.
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DR EMBL; JPKD01000166; KFZ19838.1; -; Genomic_DNA.
DR STRING; 1420914.A0A094KDY5; -.
DR HOGENOM; CLU_001482_1_0_1; -.
DR Proteomes; UP000029315; Unassembled WGS sequence.
DR GO; GO:0008061; F:chitin binding; IEA:UniProtKB-KW.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR CDD; cd02878; GH18_zymocin_alpha; 1.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 3.10.350.10; LysM domain; 2.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR029226; Ecp2.
DR InterPro; IPR036861; Endochitinase-like_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR018392; LysM_dom.
DR InterPro; IPR036779; LysM_dom_sf.
DR PANTHER; PTHR47700:SF1; CHITINASE; 1.
DR PANTHER; PTHR47700; V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR Pfam; PF14856; Hce2; 1.
DR Pfam; PF01476; LysM; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SMART; SM00257; LysM; 2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR SUPFAM; SSF54106; LysM domain; 1.
DR SUPFAM; SSF57016; Plant lectins/antimicrobial peptides; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
DR PROSITE; PS51782; LYSM; 2.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW Chitin-binding {ECO:0000256|ARBA:ARBA00022669};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000029315};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1470
FT /note="chitinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001906150"
FT DOMAIN 299..344
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT DOMAIN 363..411
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT DOMAIN 503..872
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
SQ SEQUENCE 1470 AA; 159194 MW; 491CEC3F85AB45E9 CRC64;
MVFSLWARAS LVAYGLLMAA DVVSGNPRRH AVSPTYRNSN VCPERCSDLG TNPSKWHAYH
NLEQFSACDQ AVIQAFSIYD DVDDVSKGHG IYACTSYGPD FANLPQSRVK AVIAETVDAT
YEVGWGDDGH KLAAADIRSA SKQLRKYMKG GHGSVESAEI LYARSGRAAV GLYLGKGLQK
AGVSAVALKY LEDNLSTLNA TSRDVAIQFC NPDYTSEHTF GFFATSSRTF APVQKAMQSW
ANGTCVSFPN SQTFEGQAML TAKLPTTSVS NDTVADTNST SAITSRSNYV KLNARAECST
TQVQGGDDCG KLAVRCGIAA ADFTKYNSDA SLCSTLKPGQ HVCCSAGTLP DFAPKPNADG
SCKVYYVAKD DNCSNIAAAN SLTNADLEDF NKNTWAWSGC DTLQFNMNIC LSTGDPPMPP
SQEGIVCGPQ KPGTKQPTDG TKLADLNPCA LNACCDIWGQ CGITAEFCTD TGTGNPGTAK
PGTNGCISNC GTKMVKGSAP TEFRRIAYYE GYSFGRECLF QDVLQIDPTQ YTHLHFAFGT
LTANYEVEVG DIMSSYQFEN FRRIQGPKRI LSFGGWDFST MPETYTIFRE GVTAANRLKL
ATNIANFIKE KDLDGVDIDW EYPGAPDIPG IPAASLDDGD NYLAFLVILK NLLPGKSVSI
AAPSSYWYLK AYPLKKIAAV IDYIVYMTYD LHGQWDAQNP NSQEGCANGN CLRSQVNLTE
TMSSLIMITK AEVPSNKVVV GITSYGRSFN MAQAGCHTPE CLYTGDRLNS DATKGKCTAT
AGYISDAEIK EIIDEGSRVT NHYVDPTSNS NILVYDDTQW VAYMDDSIRT QRHALYTGLN
LGGTTNWATD LEKYNDVPGD SGSWLNYKLS IKAGKNPWQV GDRTGNWTEI MCDSQAASDI
RGLTPEQRWD GMDMEDAWKD SIAVWKEYDR GKTSFTFTQS MSLTLNGPER ASCGSLKSDS
NCIQTLQCSP FQNKGSGAAA YELWNSFVII HEMYQTFNDA LYKAAATVIT PALSDFEKKF
TPVPPEEDNT WLLLLLDLVT VGISAVAAPF FNNFIAKLPY FIAKEAAANN IKDLTLLAIG
QSTTIAKDLL STKESDWTED KQDEFSNYLG QSIAAWGNTT GAALQRLFNG EDESIDALYA
IISDGKLISG GGAESSTAPP ETSEAELENH IARAFFAFAI PTGWTFSKHY AFVIDSGYDC
SASDPMGDYL DADTMHTTYG CYQNKLYYLA AAQGDSKTCH DNCNDGHCDK VCVDSKFKAP
PGLETLDGKN FGGVSVQDLI QGSVRTYLQN SNENGGAFVD ITNGGSFDDL MAIDLTTPGF
IRLPVCTPER AYKSWDTAGP KDDDPLYPCS IAKGPDHCQI SSFVDQTSDA SPPVEDCKQI
IKNIEGDGGA TWTTGISGQR QLVSYGECKF GVQSKSGADG NVTFKVGSQD IIDLINEAIK
QFGGGGKVGA KGIVDCDGNV HDTTIEWGLY
//
