ID A0A094MIT0_ANTCR Unreviewed; 829 AA.
AC A0A094MIT0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Suppressor of tumorigenicity 14 protein {ECO:0000313|EMBL:KFZ53201.1};
DE Flags: Fragment;
GN ORFNames=N321_06154 {ECO:0000313|EMBL:KFZ53201.1};
OS Antrostomus carolinensis (Chuck-will's-widow) (Caprimulgus carolinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Caprimulgiformes;
OC Caprimulgidae; Antrostomus.
OX NCBI_TaxID=279965 {ECO:0000313|EMBL:KFZ53201.1, ECO:0000313|Proteomes:UP000053620};
RN [1] {ECO:0000313|EMBL:KFZ53201.1, ECO:0000313|Proteomes:UP000053620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N321 {ECO:0000313|EMBL:KFZ53201.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; KL341480; KFZ53201.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094MIT0; -.
DR Proteomes; UP000053620; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00041; CUB; 2.
DR CDD; cd00112; LDLa; 4.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 4.
DR Gene3D; 3.30.70.960; SEA domain; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR017051; Peptidase_S1A_matripase.
DR InterPro; IPR000082; SEA_dom.
DR InterPro; IPR036364; SEA_dom_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24252:SF8; ACROSIN; 1.
DR PANTHER; PTHR24252; ACROSIN-RELATED; 1.
DR Pfam; PF00431; CUB; 2.
DR Pfam; PF00057; Ldl_recept_a; 4.
DR Pfam; PF01390; SEA; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PIRSF; PIRSF036370; ST14; 1.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00042; CUB; 2.
DR SMART; SM00192; LDLa; 4.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 4.
DR SUPFAM; SSF82671; SEA domain; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS01209; LDLRA_1; 1.
DR PROSITE; PS50068; LDLRA_2; 4.
DR PROSITE; PS50024; SEA; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Hydrolase {ECO:0000256|RuleBase:RU363034};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|RuleBase:RU363034};
KW Reference proteome {ECO:0000313|Proteomes:UP000053620};
KW Serine protease {ECO:0000256|RuleBase:RU363034};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..177
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 188..307
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 313..420
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 589..828
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT ACT_SITE 630
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR036370-1"
FT ACT_SITE 685
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR036370-1"
FT ACT_SITE 779
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR036370-1"
FT DISULFID 432..450
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 444..459
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 461..473
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 468..486
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 480..495
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 497..509
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 504..522
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 516..531
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 541..553
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 561..576
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFZ53201.1"
FT NON_TER 829
FT /evidence="ECO:0000313|EMBL:KFZ53201.1"
SQ SEQUENCE 829 AA; 92388 MW; CB50D6891A60957C CRC64;
DMNNLEEGVE FLPAMNSKKM EKRGPKRRVV VTVTIVVFLL ISLVTGLLVW HFKYRNAAVQ
KVFNGHLRVL NWEFLDAYEN SSSPEFMMLA KKVKSTVEEI YRNHADIGPY HKETVITAFS
EGSIIAYYWS EFLVPKYREE NLDRAMADKQ SLVQRWNPRL RNPMLKVESV VAFPADPSIA
SSARDNSCIF ALHAKEGEIT SFTTPGFPNS PYPNNAHCYW TLRADANSII SLTFKTLELE
QCTDNSDYIK VYNSLSPVEP HALVRLCGNY APSYNLTFLS SQNVMLVTLI TNKEGRFPGF
KAEFFQLPKM KACGGTLKGE SGTFTTPYYP AHYPPAMDCV WNIEVPSKKN VKVRFNMFYV
LEPGIPVTSC TKDYVQINST RYCGERSQFV VASTTNKIEV RFHSDQSYTD TGFSAEYLSY
DSSDPCPGKF TCNTGRCIDR SMRCDGWLDC VDGSDERSCT CTDQQFKCRN GWCKPKFWVC
DNVNDCGDNS DELQCSCAAE SFKCNNGKCV PDAQKCDGKD DCGDGSDEGS CSHAVHATIP
CKEHTYKCHS GRCISKQNPE CDGERDCEDN SDEDNCNCGI RSYTRKSRIV GGQNSDVGEW
PWQVSLHVKG QGHICGASLV SESWLVSAAH CFVQLQGIRY SDPSLWTAYL GLTDQGNRDG
ANVQTRKIKR IISHPYFNDY TYDYDIAVVE LQTPVTFSSV VQPICLPDAT HNFPVGKDLW
VTGWGATTEG GSGASILQKA EIRVINQTVC NELLTDQLTP RMMCVGILSG GVDACQGDSG
GPLVSVESSS RMFLAGVVSW GDGCAQRNKP GVYSRVTSLR AWIKEHTGL
//
