ID A0A094ZGJ0_SCHHA Unreviewed; 200 AA.
AC A0A094ZGJ0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=MAD2 mitotic arrest deficient-like 1, variant 2 {ECO:0000313|EMBL:KAH9589640.1};
DE SubName: Full=Mitotic spindle assembly checkpoint protein MAD2A {ECO:0000313|EMBL:KGB31964.1};
DE SubName: Full=Mitotic spindle assembly checkpoint protein mad2-related protein {ECO:0000313|EMBL:KAF1332297.1};
GN Name=MAD2L1_1 {ECO:0000313|EMBL:KAH9589640.1};
GN ORFNames=MS3_00002634 {ECO:0000313|EMBL:KAH9589640.1}, MS3_00092
GN {ECO:0000313|EMBL:KGB31964.1}, MS3_0016874
GN {ECO:0000313|EMBL:KAF1332297.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB31964.1};
RN [1] {ECO:0000313|EMBL:KGB31964.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
RN [2] {ECO:0000313|EMBL:KAF1332297.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=31494670;
RA Stroehlein A.J., Korhonen P.K., Chong T.M., Lim Y.L., Chan K.G.,
RA Webster B., Rollinson D., Brindley P.J., Gasser R.B., Young N.D.;
RT "High-quality Schistosoma haematobium genome achieved by single-molecule
RT and long-range sequencing.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EMBL:KAH9589640.1}
RP NUCLEOTIDE SEQUENCE.
RA Stroehlein A.J.;
RT "Chromosome-level genome assembly for S. haematobium.";
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:KAH9589640.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=35167626;
RA Stroehlein A.J., Korhonen P.K., Lee V.V., Ralph S.A., Mentink-Kane M.,
RA You H., McManus D.P., Tchuente L.T., Stothard J.R., Kaur P., Dudchenko O.,
RA Aiden E.L., Yang B., Yang H., Emery A.M., Webster B.L., Brindley P.J.,
RA Rollinson D., Chang B.C.H., Gasser R.B., Young N.D.;
RT "Chromosome-level genome of Schistosoma haematobium underpins genome-wide
RT explorations of molecular variation.";
RL PLoS Pathog. 18:0-0(2022).
CC -!- SIMILARITY: Belongs to the MAD2 family.
CC {ECO:0000256|ARBA:ARBA00010348}.
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DR EMBL; AMPZ02000254; KAF1332297.1; -; Genomic_DNA.
DR EMBL; AMPZ03000002; KAH9589640.1; -; Genomic_DNA.
DR EMBL; KL250488; KGB31964.1; -; Genomic_DNA.
DR RefSeq; XP_012791749.1; XM_012936295.1.
DR AlphaFoldDB; A0A094ZGJ0; -.
DR STRING; 6185.A0A094ZGJ0; -.
DR EnsemblMetazoa; XM_012936295.2; XP_012791749.1; MS3_0016874.
DR OrthoDB; 5474106at2759; -.
DR Proteomes; UP000471633; Unassembled WGS sequence.
DR Gene3D; 3.30.900.10; HORMA domain; 1.
DR InterPro; IPR003511; HORMA_dom.
DR InterPro; IPR036570; HORMA_dom_sf.
DR InterPro; IPR045091; Mad2-like.
DR PANTHER; PTHR11842; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; 1.
DR PANTHER; PTHR11842:SF11; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A; 1.
DR Pfam; PF02301; HORMA; 1.
DR SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
DR PROSITE; PS50815; HORMA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Reference proteome {ECO:0000313|Proteomes:UP000471633}.
FT DOMAIN 12..194
FT /note="HORMA"
FT /evidence="ECO:0000259|PROSITE:PS50815"
SQ SEQUENCE 200 AA; 22627 MW; DA8D55E9CB15247A CRC64;
MSTETSSSIS LKGSAELLTD YFFYALNSIL YQRGIYPSAS FKQNIKYDLS VLVTTDENLI
KYLNVILNQV KNWLEDGSVH RLALIIKSVK TDEVLERWQF DMTTEKTDTS NSVGTKSLAQ
IQSEIQGVIR QIVASNTFLP VLNSSCTFEL LVYADRNANV PTSWEETGPQ FIVNSTEIKL
RSISTTLHRV DHTVSYKRSI
//
