ID   A0A094ZWL7_SCHHA        Unreviewed;      1279 AA.
AC   A0A094ZWL7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Tensin-3 {ECO:0000313|EMBL:KGB37569.1};
GN   ORFNames=MS3_05915 {ECO:0000313|EMBL:KGB37569.1};
OS   Schistosoma haematobium (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB37569.1};
RN   [1] {ECO:0000313|EMBL:KGB37569.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22246508; DOI=10.1038/ng.1065;
RA   Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA   Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA   Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA   Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA   Wang J., Gasser R.B.;
RT   "Whole-genome sequence of Schistosoma haematobium.";
RL   Nat. Genet. 44:221-225(2012).
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DR   EMBL; KL250901; KGB37569.1; -; Genomic_DNA.
DR   RefSeq; XP_012797331.1; XM_012941877.1.
DR   AlphaFoldDB; A0A094ZWL7; -.
DR   STRING; 6185.A0A094ZWL7; -.
DR   CDD; cd09927; SH2_Tensin_like; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR035012; Tensin-like_SH2.
DR   PANTHER; PTHR45734:SF7; EGFR ADAPTER PROTEIN-RELATED; 1.
DR   PANTHER; PTHR45734; TENSIN; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW   ProRule:PRU00191}.
FT   DOMAIN          914..1024
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   REGION          412..433
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          777..800
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1279 AA;  144662 MW;  EFD95456C7C3F4CD CRC64;
     MTTELCKEMK RNQYIENHEL YSNPYQNNST GNNPYNSEIY SKVDHERNVL HPHLHAPLSY
     VVHNPHAIKL KRSCHNTKCR YCFPNASNNN PFDLESHSSS SESASQIMTR SALNNHSNYK
     KFLGLNKRPT CIIHEETTVN DSRQDVINGG QVKIRQENEI PVFKEVRTST PLVNHTTLPN
     RTNNYIPNLI KNNYHLEDHQ EVYWSEQETP FTVYSNASIN TNSNHNSIVV TGRQAGLFNQ
     KNPNRVIQNE SIATPTNTTE TSMTTNVSIE NEMLSKTTTN NLYKKEGNTF LQKIFKKPQS
     TIIEENNKLR LRLTSLTNSP ENNQSIPCTE ITTTPYSLNM HDLQKHNNHN HDPDRDDLSV
     IFAIYKSQII SNDGNFSAPK RAMSHTNVYG PRSWNLRSYQ GSESDLAYKR EMLSSSSSSR
     LARSGYSARR ERLKQEREQE LLRQTRLRQM AASSTGLHDH RHYQQSNIQQ QHYRSTSAVN
     RSMGNTEAFE EFETITLQPI GRGVQDLDSH VGSMTTLARG GGASSMIEVH KHTFRTPRMY
     SPTSYHFNRA HSTTPTRYSR PTKGFSNGLY KSHSAYSGSV ETCPMFKSHT PDPGRDITGS
     PLWTALPRNS STTPTICKTW RSERNITTTP LGQITYEDVM PNTQMAKIQV LESSELPTTF
     SPYSRKSASL QPNEVVKKDI RVFESPSDNA ILNNYLDIHE SEMTNLKRVV SLRKPPERSR
     LWALPDNMKI LRSSDGFMAD SCYPNDVDID ENEELINHQF NLPEPGKTTL KTEINGLSRI
     DDHQPPRASS RTSLSRQPFD STQYLNKQNY NHDGEQTIFI NRVQPTSSTP VQSYPPSRLG
     TQSVYSDHIT VSTTPQTVTA PTKVVSNLNV LTNTRKTSEL TEVPMQNGWK SEKPKQDTVD
     SGNMPQVIAT ARVWYQPKLS REEAISILRQ QVPGSFLIRD STTYKDAFGL AVKVATLPPK
     VTPKSNDLQS ELVRHYLIEA VNTPTKGVRL KGFASEPVFP SLAALINRHT QDALALPCRL
     ILPAIPTTPL PHGYKPPPQI VTGLPPNTTD TTISNHISQS NNQYISKVDS ATGPVSELGS
     VIMDNVEIDC TKSVTNTSTM GIEGLPFECV IKDEHHKPVM SQCLLNQGMT YRCFMLGSVD
     TPQWNNELCF SRAVDQLIPL ETLTASECDH GISRVRYSDI QLHVSAHDGI TIIDLLRRLF
     LRRHLPNNIL LYCGIETRKK EFIHPEHQNH GIRNPKIFGL VVRKGISECT CHIFSECDPV
     HSAESIVNYI RTIYPHLKS
//