ID A0A095A330_SCHHA Unreviewed; 517 AA.
AC A0A095A330;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Putative splicing factor 3a {ECO:0000313|EMBL:KAF1317171.1};
DE SubName: Full=Splicing factor 3A subunit 3 {ECO:0000313|EMBL:KAH9593906.1, ECO:0000313|EMBL:KGB41217.1};
GN Name=SF3A3 {ECO:0000313|EMBL:KAH9593906.1};
GN ORFNames=MS3_00002459 {ECO:0000313|EMBL:KAH9593906.1}, MS3_0015512
GN {ECO:0000313|EMBL:KAF1317171.1}, MS3_09721
GN {ECO:0000313|EMBL:KGB41217.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB41217.1};
RN [1] {ECO:0000313|EMBL:KGB41217.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
RN [2] {ECO:0000313|EMBL:KAF1317171.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=31494670;
RA Stroehlein A.J., Korhonen P.K., Chong T.M., Lim Y.L., Chan K.G.,
RA Webster B., Rollinson D., Brindley P.J., Gasser R.B., Young N.D.;
RT "High-quality Schistosoma haematobium genome achieved by single-molecule
RT and long-range sequencing.";
RL Gigascience 8:0-0(2019).
RN [3] {ECO:0000313|EMBL:KAH9593906.1}
RP NUCLEOTIDE SEQUENCE.
RA Stroehlein A.J.;
RT "Chromosome-level genome assembly for S. haematobium.";
RL Submitted (JUN-2021) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:KAH9593906.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=35167626;
RA Stroehlein A.J., Korhonen P.K., Lee V.V., Ralph S.A., Mentink-Kane M.,
RA You H., McManus D.P., Tchuente L.T., Stothard J.R., Kaur P., Dudchenko O.,
RA Aiden E.L., Yang B., Yang H., Emery A.M., Webster B.L., Brindley P.J.,
RA Rollinson D., Chang B.C.H., Gasser R.B., Young N.D.;
RT "Chromosome-level genome of Schistosoma haematobium underpins genome-wide
RT explorations of molecular variation.";
RL PLoS Pathog. 18:0-0(2022).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SF3A3 family.
CC {ECO:0000256|ARBA:ARBA00008776}.
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DR EMBL; AMPZ02000558; KAF1317171.1; -; Genomic_DNA.
DR EMBL; AMPZ03000001; KAH9593906.1; -; Genomic_DNA.
DR EMBL; KL251768; KGB41217.1; -; Genomic_DNA.
DR RefSeq; XP_012800981.1; XM_012945527.1.
DR AlphaFoldDB; A0A095A330; -.
DR STRING; 6185.A0A095A330; -.
DR EnsemblMetazoa; XM_012945527.2; XP_012800981.1; MS3_0015512.
DR GeneID; 24595214; -.
DR CTD; 10946; -.
DR OrthoDB; 5483967at2759; -.
DR Proteomes; UP000471633; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR InterPro; IPR000690; Matrin/U1-C_Znf_C2H2.
DR InterPro; IPR025086; SDE2-like_C_dom.
DR InterPro; IPR031774; SF3A3_dom.
DR InterPro; IPR024598; SF3a60/Prp9_C.
DR InterPro; IPR021966; SF3a60_bindingd.
DR PANTHER; PTHR12786:SF2; SPLICING FACTOR 3A SUBUNIT 3; 1.
DR PANTHER; PTHR12786; SPLICING FACTOR SF3A-RELATED; 1.
DR Pfam; PF13297; SDE2_2C; 1.
DR Pfam; PF16837; SF3A3; 1.
DR Pfam; PF12108; SF3a60_bindingd; 1.
DR Pfam; PF11931; SF3a60_Prp9_C; 1.
DR PROSITE; PS50171; ZF_MATRIN; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000471633}.
FT DOMAIN 422..453
FT /note="Matrin-type"
FT /evidence="ECO:0000259|PROSITE:PS50171"
FT REGION 362..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 60382 MW; 04086AE7C00CFD92 CRC64;
METVLEQQRR IHEERERLIN ELTKEMLYNP TTHREKLNSE LRLRLMYDRY FDVTQELRDL
YEDKDGLRKA DIQTLSGPNE FNEFYDRLKQ IKEFHRKHPG EICVPMSAEF EKYKEMRERP
EEANAVLIDF SDEEGYGRYL DLHDVYKKYL NVKGVPRIDY LTYISFFDRL YDISRDKKGI
AYKAYLEELL GYLENFVSRA RPIVDLEEET KEALAKFETQ WTQGTFPGWG REAASALAHG
GAHLDLTAFT AWEELASLGL DRLKSALLAL GLKCGGTLEE RARRLWATKG KSLEELPADL
FVTKQRSTKG FAKTAAWGHV PPALSEKLKE IATLEARIYR LSELVKEHRE ATIENVQRRQ
ARIGFERDED DTDADKDATG AENGQNEEDD DIPYNPKNLP LGWDGKPIPY WLYKLHGLNM
YYSCEICGNQ TYRGPKAFQQ HFSEWRHAHG MRCLGIPNTI HFAHVTKIEE ALALWQRIRT
MKEAERWRPE VEEELEDSVG NVVSRKTYED LKRQGLL
//
