ID A0A095AW96_SCHHA Unreviewed; 715 AA.
AC A0A095AW96;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Tubulin-specific chaperone E {ECO:0000256|ARBA:ARBA00015004};
DE AltName: Full=Tubulin-folding cofactor E {ECO:0000256|ARBA:ARBA00030180};
GN ORFNames=MS3_07310 {ECO:0000313|EMBL:KGB38901.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB38901.1};
RN [1] {ECO:0000313|EMBL:KGB38901.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TBCE family.
CC {ECO:0000256|ARBA:ARBA00006286}.
CC -!- SIMILARITY: Belongs to the U2 small nuclear ribonucleoprotein A family.
CC {ECO:0000256|ARBA:ARBA00024196}.
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DR EMBL; KL251095; KGB38901.1; -; Genomic_DNA.
DR RefSeq; XP_012798661.1; XM_012943207.1.
DR AlphaFoldDB; A0A095AW96; -.
DR STRING; 6185.A0A095AW96; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd17044; Ubl_TBCE; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR044079; Ubl_TBCE.
DR PANTHER; PTHR10552; U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A; 1.
DR PANTHER; PTHR10552:SF6; U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
DR PROSITE; PS51450; LRR; 1.
PE 3: Inferred from homology;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614}.
FT DOMAIN 69..113
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 624..645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 81258 MW; E62AE38D1D23A1F2 CRC64;
MTFVFNCIEG QQHYTSTFSM NTTSNAHSHS PIKDVYLGTE CGKIAEVNEL IIGRRIVHEK
NFGTICYVGE LPRSNGSWLG VDWDDQSRGR HDGTYDDVRY FQAKCPTSGS FVRPSKVSLG
TSLEEALVYR YAVCTTCQLE IQTSLRSREK PTGSSHNILV HECTQLGHLN SYLGSTAEEA
EYFGTHGYPK DTLRVELYTN PGTYHQSTSH DELCGADAAK SCLSRLNSVS LSSVPVYRAL
YGKSNFFPDR QPEYSPLWPS SGGCLDQFLS SLCDLEMSNC LLSKWTEIAE ICIQIPWLKS
LNVSNNRIRL PVSPKEAHDK QKENECLESR LLYDIYSDPV LSERLCSNAF PQLSQLTLVK
CSLLNWKSIR RILCWMPSLQ SLSLAYNNLG NPPIDWEENA IEVFQKLTEL DLTHINLTSA
HQLFALIGAS KCLNSLLLNY NEIADIPNLN DHSKHICQIH VHDKDSSHLF RNLNTLGLKN
NLFTNWNFVN QLLHLSKLDH LMVSGCPVFE NSVSIETARQ EVIARLPNLK MLDRVEITPE
ERRGSELDYL KRYGASWLNC CKSDQNSKQN NDVKLLEEFY KLHPVFSRLC DKHGAPEIGE
TKPVNRSIKA GLLSLIFILQ HNKNSGATNK PSSRSSSPMD KNDRIQKQIP SQMTINHLRM
MIRRLFCLSP KTLFELYAQS GRHRGIVNTE IPLDVDTREI GFYNLENDDY IFIRI
//
