ID A0A095AYQ6_SCHHA Unreviewed; 309 AA.
AC A0A095AYQ6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Secreted frizzled-related protein 2 {ECO:0000313|EMBL:KGB39856.1};
GN ORFNames=MS3_08312 {ECO:0000313|EMBL:KGB39856.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB39856.1};
RN [1] {ECO:0000313|EMBL:KGB39856.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00090}.
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DR EMBL; KL251304; KGB39856.1; -; Genomic_DNA.
DR RefSeq; XP_012799614.1; XM_012944160.1.
DR AlphaFoldDB; A0A095AYQ6; -.
DR STRING; 6185.A0A095AYQ6; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.10.2000.10; Frizzled cysteine-rich domain; 1.
DR InterPro; IPR015526; Frizzled/SFRP.
DR InterPro; IPR020067; Frizzled_dom.
DR InterPro; IPR036790; Frizzled_dom_sf.
DR PANTHER; PTHR11309; FRIZZLED; 1.
DR PANTHER; PTHR11309:SF148; SECRETED FRIZZLED-RELATED PROTEIN 1; 1.
DR Pfam; PF01392; Fz; 1.
DR SMART; SM00063; FRI; 1.
DR SUPFAM; SSF63501; Frizzled cysteine-rich domain; 1.
DR PROSITE; PS50038; FZ; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00090}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 142..264
FT /note="FZ"
FT /evidence="ECO:0000259|PROSITE:PS50038"
FT DISULFID 157..203
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 226..250
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
SQ SEQUENCE 309 AA; 35212 MW; 8E3ACB879E5FBA18 CRC64;
MKTITFLINL WIINFSIILS CYYVNSTVYS YPLHIFGRIG LTSASKQPFL SSWNSKYIKN
HDNYSKRNYL HNDLLFNDHD SSSSSSSSVS SSTALSSPTS SLSSSLLLDE NFFDIHNTHS
SNIDRLDPTS YYADWHRLLN GYGSQRCHKI PKNMSLCQNI GYDGMILPNY LQHEDLKEAV
EQSQVWTSLA QTECHSDLRK FLCALYAPVC VDGHQERLIH PCQNLCEDVR RSCLPKMLQF
GFGWPDIVKC SRFPTSATRM CIPLTQQRKG NNNNSNNDNI LIVLSSAHRS FRLLASLLPH
KKQTNIITS
//
