ID   A0A095BU91_SCHHA        Unreviewed;       724 AA.
AC   A0A095BU91;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   08-NOV-2023, entry version 30.
DE   SubName: Full=Pleckstrin homology domain-containing family G member 7 {ECO:0000313|EMBL:KGB32443.1};
DE   Flags: Fragment;
GN   ORFNames=MS3_00575 {ECO:0000313|EMBL:KGB32443.1};
OS   Schistosoma haematobium (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB32443.1};
RN   [1] {ECO:0000313|EMBL:KGB32443.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22246508; DOI=10.1038/ng.1065;
RA   Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA   Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA   Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA   Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA   Wang J., Gasser R.B.;
RT   "Whole-genome sequence of Schistosoma haematobium.";
RL   Nat. Genet. 44:221-225(2012).
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DR   EMBL; KL250503; KGB32443.1; -; Genomic_DNA.
DR   RefSeq; XP_012792216.1; XM_012936762.1.
DR   AlphaFoldDB; A0A095BU91; -.
DR   STRING; 6185.A0A095BU91; -.
DR   EnsemblMetazoa; XM_012936762.2; XP_012792216.2; MS3_0018997.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   CDD; cd13245; PH_PLEKHG7; 1.
DR   CDD; cd00160; RhoGEF; 1.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR040181; PKHG5/7.
DR   PANTHER; PTHR13217; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7; 1.
DR   PANTHER; PTHR13217:SF6; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7; 1.
DR   Pfam; PF16652; PH_13; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50010; DH_2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
FT   DOMAIN          311..505
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   DOMAIN          559..684
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KGB32443.1"
FT   NON_TER         724
FT                   /evidence="ECO:0000313|EMBL:KGB32443.1"
SQ   SEQUENCE   724 AA;  83931 MW;  0C7F5189D881E412 CRC64;
     DEINNNTDTT NNKQVVNIIT HKTNCNENNS TINRKDSVHN DSSENMMKIS ITNGFWPGNP
     YSPLPSPDIS ILDSDLNDNH FILDTELTND DKNLQRHESW QSLELDTVPS SSGTGEVESL
     STKTVITTTP TTTTKNITNE NNTEFIINNQ DGQDNEQIDL ASRRGRRSAI IDKKNLIGET
     EVENQDTTTI SQNVNKNLNE TGQERPPITS SVNSFRERQK RILRKQNTIS DLSCRNQITN
     TNQDYELKRR ANVFMKLIER GTRSKDLNEA LQSLKPSYFH DQYLESFRDS HWSQLDKSGN
     SENTMTDREV RRCEAVWELF KSELTFFTDH LMVLKNCFME PLKKLQVDGY LMFVEPMHLF
     GNLDDLCYVS HTFCRELISN LSQESVSNEF GSTDVLLRPL KRWSEHSKDG EIYHNYCLNY
     DSALNYLDSL RKLEHFNEFE KWCEQDTRCR RLQLTDLLVA PMQHYMKIPL LLSSIRRYTA
     CSAEQEMLTA CLTKVENSLK SLEDKMRWLK NFERLQEIQS QLIWPSVSEL EPRVFIPEFL
     RQSLIRQPCE RLIANPKRQL LHEGFLTLND GTKTIEIFAF LFDDFLLVTR IKKPPKKKSF
     SENPLTGRSL TEGGVFVVYR QVIALDRFTI HDLGIVEATA NGLRNAIVLV LITRFQQITG
     VYTLQAANEL DKQRWIEKLR NSQQAFQEKL KRKLYGIDMD QHTNKHSKLI NAKNKLPNQT
     SIAD
//