ID A0A095BZ79_SCHHA Unreviewed; 813 AA.
AC A0A095BZ79;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Pendrin {ECO:0000313|EMBL:KGB34498.1};
GN ORFNames=MS3_02707 {ECO:0000313|EMBL:KGB34498.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB34498.1};
RN [1] {ECO:0000313|EMBL:KGB34498.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
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DR EMBL; KL250614; KGB34498.1; -; Genomic_DNA.
DR RefSeq; XP_012794260.1; XM_012938806.1.
DR AlphaFoldDB; A0A095BZ79; -.
DR STRING; 6185.A0A095BZ79; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR018045; S04_transporter_CS.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00815; sulP; 1.
DR PANTHER; PTHR11814:SF257; ANION TRANSPORTER SULP-7D; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS01130; SLC26A; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 259..279
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 314..332
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 344..365
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 402..420
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 470..487
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 531..549
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 592..789
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 813 AA; 92831 MW; 76FAB55E3DFF7C61 CRC64;
METVRGQSDS NDINEHNTLI SINRPLFTKE TFHQYAGYKS NLKSLTTWQQ CLHIFMPFIQ
KCSQILRVNT NENTYKDREE TNEEFSKKSR KQSIIDNCQY FMTRFFKWLI TYFPFIQILM
QYRVKSWLFN DIISGFTVGI MHVPQGMAYA LVATLPPVYG LYTSFFPSLI YFFLGTSRHI
SIGTMAVVSL LTGDFLDRVI HLKADSIKSA NEALYGNMTH NDTSLHDAEQ FRIPYALALG
FSVGIVQLLM GLFRLGSLIR YFSVPMTSGF TVGVAVHVFT TQVKNVLGLK LPRFPGLFTI
PYTYYEIFRT IQHTNIPTML MAGACIAILA VYKERISPVV KKFSFIPLPI DLIIVILSTI
VSYSVDLHDK YDVKIVGKIS KGIQYPEVPD ITLMGPHIGD SIISAVIGIS VSVSLARIFA
TRFNYKINTN QELIAFGVTN VISSFFHGYP AAASLSRSAV AVSAGGRTQV ASLFSCLLLI
LVLFFIGPLL FSVPIFCLSA IIIVAIKGMF MEAKDLVMFW RFSPWDSVRN ILKRFNAVWI
FTFLCTVLLS VNYGLLLGII ISVGVVILRI QWPKIHSFEQ IQNTEIYRNS RDYTNYIKHD
KIKIIRYEGN LFYFCAEHFR ETVYLQTGIN PFDINLKVNS CLNRIKQIEN TLRSTSKSMD
IEIDKSDDHS NEIKTIEETS DQLEACRKLL TLNEKSKLEM ERIKQIEKLE IINHLLTFNY
LILDCSCWTF IDIVGADELK QVIDSYEKLG IIVLLAQMKD YLIHTLQNND KLGDLTKIYP
TVHDAVNDAI IQLNTMKVKE RNFLQLNEET LTS
//
