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Database: UniProt
Entry: A0A095C1W1_CRYGR
LinkDB: A0A095C1W1_CRYGR
Original site: A0A095C1W1_CRYGR 
ID   A0A095C1W1_CRYGR        Unreviewed;      2006 AA.
AC   A0A095C1W1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   07-JUN-2017, entry version 21.
DE   SubName: Full=High-affinity cell membrane calcium channel {ECO:0000313|EMBL:KGB74940.1};
GN   ORFNames=CNBG_0778 {ECO:0000313|EMBL:KGB74940.1};
OS   Cryptococcus gattii serotype B (strain R265) (Filobasidiella gattii)
OS   (Cryptococcus bacillisporus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
OC   Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus gattii species complex.
OX   NCBI_TaxID=294750 {ECO:0000313|EMBL:KGB74940.1, ECO:0000313|Proteomes:UP000029445};
RN   [1] {ECO:0000313|EMBL:KGB74940.1, ECO:0000313|Proteomes:UP000029445}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R265 {ECO:0000313|EMBL:KGB74940.1,
RC   ECO:0000313|Proteomes:UP000029445};
RX   PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA   D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA   Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T.,
RA   Sawkins J., McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q.,
RA   Bartlett K., Li W., Wang X., Heitman J., Stajich J.E., Fraser J.A.,
RA   Meyer W., Carter D., Schein J., Krzywinski M., Kwon-Chung K.J.,
RA   Varma A., Wang J., Brunham R., Fyfe M., Ouellette B.F., Siddiqui A.,
RA   Marra M., Jones S., Holt R., Birren B.W., Galagan J.E., Cuomo C.A.;
RT   "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT   immunocompetent hosts.";
RL   MBio 2:E342-E342(2011).
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DR   EMBL; KQ410558; KGB74940.1; -; Genomic_DNA.
DR   EnsemblFungi; KGB74940; KGB74940; CNBG_0778.
DR   OMA; MLGDSAM; -.
DR   Proteomes; UP000029445; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   Pfam; PF00520; Ion_trans; 4.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000029445};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029445};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    301    324       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    344    368       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    473    491       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    534    554       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    637    658       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    670    695       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    805    831       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    851    876       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    934    959       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1159   1182       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1203   1222       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1242   1262       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1303   1328       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1418   1440       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1496   1515       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1530   1548       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1560   1579       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1632   1653       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1665   1682       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1726   1747       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      464    702       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      740    969       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1166   1445       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1498   1748       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   2006 AA;  226250 MW;  3ACC5CC0077BA97B CRC64;
     MSHSRNHSLA ISTSASIHTS PSPSPVSPAS PGSASAGLSR RHSWNITEEN QELPTFHESG
     NSSRHVDGNP TPRRAVPLHS TPLGKSGTAH SHRLSERDIA WAGVNDGTAV WGDLDHTTPT
     QSRSRPLFNT YQSTTSLQST VWPLDDHGRS SDDRERLTSG PSQIMEYNGI GKGTPRRSPR
     KPYNESGSAL GRSSTLRNVS QSLRKASVRV VNIMGTERGD GRERLGSDDE GEEVLQDVEI
     DGDQGFVMSS TNDNQGTVPS PRRSPTRSQR EEAGRRRLRG RTMCVFGPTS RVRKSMDRLM
     MYPWTEPVIL LLIITNVVVL AIQSAPTLNS PRIDDGYFQA WEDVVLLVLF IVFTLEMFAR
     IVVTGLLLDP ETSLRESLFG QDGVVAVLQQ YLLITKSNIE SNLRRKATKK RAPWRSQGQN
     DATHNTDSKT PPTTSALRSL TGLSEAPFQK AMAKQKGLSD QGRPYLRHSW HRIDMIAVFA
     FWIMFFLALT GHEATADRHI YIFRALSILR AGRLLVITSG TTTILHSLKR AGPMLITVSY
     FLVFAACIFS IIGVQSFRGS FRRACMLTDP HNSSNVIQLQ TQCGGWLNST SLESVSYLNL
     DGTSSAVPPK GYICPLGQIC MTTDENPNNN VNSFDNVFSS LVQIIIITSI NTWAPVMYMA
     MDSDFFASSL FFIAGVIVLN FWLINLLIAV VVNTFSDIRA ETKRSAFGAG ETFLGTEPHW
     AAEDEKTKVN RLLAFYQKTE IFWVILIVAD LVTQGTKTSS SSESMLRLLD HLELAFTLAF
     DLEIMIRFLA YLPDWRSFFY RKRNCFDLFL AIACSVIQIP VISNSTIYPW LTVFQLIRWY
     RVILAFPRMK PLLVTVFGSF GGLLNMVIFL FLMNFLGALM ALQLFRGDVE AGETITFSQT
     YNSFLGMYQI FSSENWTDIV YNTMGAEAQY KQNVIAAIFL CGWFLFSNFI VLQMFIAVIN
     ENFAIAEEQK RKQQLQAFIH RAEAPSAHAS WIERLNPYRL MTAHHRAVKV DTLPPNLILP
     LKQNVGIDVS SSLPMDDGKG TKVTVKRLLG RDHDEDRIAL KRLKRPSPRE FTDDVEDEDD
     DRGLTDLLPP LNAAVSTDEH MDALRERRNQ QADFIAAHPS YDKSLWLFKQ SNPIRRFCQA
     CVPPAYGERI FGRPANPTLA LMVKTVVFLA VVASIVVAAI ASPSYRREYY ADHGIFRGTW
     FDLTEVALGS IFVLEAAMKI VADGFIFAPN AYLLSLWNVL DFIILITLLI NITTSLIFIG
     GLSRVTRALK SFRALRLITL FGRLRDTLHA VLFAGALKIL DASIFMILYL IPFAVWGLNI
     FSGLLYYCND DNASGLTSCI GEFSTSSVDD SLTYLVPRVW VNPTVDQSIW SFDSFRESIL
     ILFEIVSLEG WIDVMASVMN IVGRDQQPQD QASQWNAIYL LIFNLFGGVI ILTLFVSIII
     KNFSTRSGNA LLTTEQRQWV DLSKFIKAQT PSQLPKGRPR LPFRAWCYDR TVNKNGFWAV
     GFTMIYYLHI LLLMMEDFSE NLLNEVQLDW IFLFLTVLYA VDLLARFYGL GFKSFKSNGW
     NIFDLIVITG SFATTIPALQ ADSSGGVANQ ANVQLQKLFL VSISLKLVQR ISSLNQLFKT
     SVASLPAIGN LFLLWATIFI FYAILYLEVF GLTKEGNNAG TRFQNYYTFG NALLMLAFMS
     TGEGWNGYMH DYTIQVPRCT ENGNFLESDC GSAPGAYVLF ISWNIISMYI FVNMFTGVVV
     ESFAYVYQMP GKSSLNREEM RAFKQLWAEF DSQRVGYIKR KDLVKFFSRL TGVFEVRPYP
     VEFKIHNIIR HSRPDQVNNA SVVRGVKHAV DIRRVAEQIA QIDYRQVRER RQLFSRLYNE
     ARISEEPGKG ISFTAMLDDL LLRRAKTERV TDLVNLDRVR GLLRTIYWRK RFLATRDARK
     LTLNAEAEAQ EKGENFPTPV TSAEIRPPTS FFHSTKTHPH LTAAICHLMM STTDGMFLTR
     LFQLSKLYVD SIRSDMMREA VDHEGI
//
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