ID A0A095CAS7_CRYGR Unreviewed; 419 AA.
AC A0A095CAS7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=D-serine dehydratase {ECO:0000313|EMBL:KGB76714.1};
GN ORFNames=CNBG_2552 {ECO:0000313|EMBL:KGB76714.1};
OS Cryptococcus gattii serotype B (strain R265) (Filobasidiella gattii)
OS (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=294750 {ECO:0000313|EMBL:KGB76714.1, ECO:0000313|Proteomes:UP000029445};
RN [1] {ECO:0000313|EMBL:KGB76714.1, ECO:0000313|Proteomes:UP000029445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R265 {ECO:0000313|EMBL:KGB76714.1};
RX PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 2:E342-E342(2011).
RN [2] {ECO:0000313|EMBL:KGB76714.1, ECO:0000313|Proteomes:UP000029445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R265 {ECO:0000313|EMBL:KGB76714.1};
RX PubMed=29507212;
RA Yadav V., Sun S., Billmyre R.B., Thimmappa B.C., Shea T., Lintner R.,
RA Bakkeren G., Cuomo C.A., Heitman J., Sanyal K.;
RT "RNAi is a critical determinant of centromere evolution in closely related
RT fungi.";
RL Proc. Natl. Acad. Sci. 115:3108-3113(2018).
CC -!- SIMILARITY: Belongs to the DSD1 family.
CC {ECO:0000256|ARBA:ARBA00005323}.
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DR EMBL; CP025766; KGB76714.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A095CAS7; -.
DR STRING; 294750.A0A095CAS7; -.
DR VEuPathDB; FungiDB:CNBG_2552; -.
DR HOGENOM; CLU_031639_0_0_1; -.
DR OMA; WPRFYGW; -.
DR Proteomes; UP000029445; Chromosome 8.
DR GO; GO:0016829; F:lyase activity; IEA:UniProt.
DR CDD; cd06817; PLPDE_III_DSD; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR Gene3D; 2.40.37.20; D-serine dehydratase-like domain; 1.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR026956; D-ser_dehydrat-like_dom.
DR InterPro; IPR042208; D-ser_dehydrat-like_sf.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR28004:SF2; D-SERINE DEHYDRATASE; 1.
DR PANTHER; PTHR28004; ZGC:162816-RELATED; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR Pfam; PF14031; D-ser_dehydrat; 1.
DR SMART; SM01119; D-ser_dehydrat; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 3: Inferred from homology;
FT DOMAIN 302..403
FT /note="D-serine dehydratase-like"
FT /evidence="ECO:0000259|SMART:SM01119"
SQ SEQUENCE 419 AA; 45784 MW; 51FCE7AFFC47AE70 CRC64;
MSTFTSLSLY SLPSKSALVD EFVGQPLSAL RTPALIVDRK KFKDNCERVA SNAKERGMKF
RAHVKTHKTT EGTRMQVEAA GGVKATIAST MVEVWQIIEA GFVKEGLVDD ILYSMPISSD
KLEDINSAQE IVGKQATIRI MVDHAEQIKI LQAFSQKIQR PIKWSVFVKV DGGGKRAGAP
AESEQMKELI QALIESQDYI EIFGFYSHFG QSYASDSLSA GSSYFAGEIN CVQTAAKIAR
NLGAKGKWIL SVGATPTAHA AVQEAVKEHG GLEGELELHA GCYCMCDLQQ CATSLVSYSQ
VAISVLGRVV SVYPLRKEAM CDVGALSVSK DTGRFPGFGR VVKPDYATGW DLGRISQEHG
TLVHRQGENI KEENELKIGD SVQIIPQHAC LVCACFPWLY VVDDGGDEVV DVWVPWKGW
//
