ID A0A095CGG5_SCHHA Unreviewed; 796 AA.
AC A0A095CGG5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Spectrin beta chain {ECO:0000313|EMBL:KGB42058.1};
GN ORFNames=MS3_10641 {ECO:0000313|EMBL:KGB42058.1};
OS Schistosoma haematobium (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6185 {ECO:0000313|EMBL:KGB42058.1};
RN [1] {ECO:0000313|EMBL:KGB42058.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22246508; DOI=10.1038/ng.1065;
RA Young N.D., Jex A.R., Li B., Liu S., Yang L., Xiong Z., Li Y.,
RA Cantacessi C., Hall R.S., Xu X., Chen F., Wu X., Zerlotini A., Oliveira G.,
RA Hofmann A., Zhang G., Fang X., Kang Y., Campbell B.E., Loukas A.,
RA Ranganathan S., Rollinson D., Rinaldi G., Brindley P.J., Yang H., Wang J.,
RA Wang J., Gasser R.B.;
RT "Whole-genome sequence of Schistosoma haematobium.";
RL Nat. Genet. 44:221-225(2012).
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DR EMBL; KL252374; KGB42058.1; -; Genomic_DNA.
DR RefSeq; XP_012801881.1; XM_012946427.1.
DR AlphaFoldDB; A0A095CGG5; -.
DR STRING; 6185.A0A095CGG5; -.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR CDD; cd21248; CH_SPTB_like_rpt2; 1.
DR CDD; cd00176; SPEC; 2.
DR Gene3D; 1.20.58.60; -; 2.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00435; Spectrin; 3.
DR SMART; SM00033; CH; 1.
DR SMART; SM00150; SPEC; 3.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..51
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 72..177
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT COILED 757..791
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 796 AA; 93457 MW; A3C59B72D402EB97 CRC64;
MRIHCLENID KSLFFLSNFG VHLENIGAHD IVDGNARITL GLLWMIILRF QIQDIIFLEK
VDPLGIKSDV QRYSKEALLL WCQLKTAGYR NVDVQNFTTS WRDGLAFNAL IHRHRPDLVN
FNELSVNTPL QNLESAFIVA EKNLGISRLF DPEDIYVQQP DEKSIVTYVA TYYHYFSKMK
SETVRARRLE KFITYWRDLQ NSFDWYERRA SDLLSWIAKT VLWLNDRRFP NQVEEIQQIM
VSFKEYRLQE KSDKFNEKGE LEAHFLLTRT KMRTLGLRNY IPSTEAQISQ LNRAWNALEK
AEYGREIALR EALDKQKRLL HLFTRYEKKA NLRKAWINDN FKLVEVCDDD KNLAMTEASL
KKYEALKADI YAYFDRIQTI QQIADELIAA IEERLKQYEL IETDIRSIHR NISTLFELES
QIEYSPELFG FKTNTVAIEI KKQNNLLKDA YSQLVQLIES KQRSIEFLKL YHGSEYELDE
QLISIEERIS FLQKSEAFVD NGNIDVFFRR HKAAESELET QRLIITRLFE RTSSLIEEEC
PNYENLKEKV TKVEKAWEQL INLMAKRKTN LLFMKDLRSF VLSCDDADAW ISEKYELSSS
AMRLAMQTDS IYTIEKLTKQ HQETISSVNN FQTTIDQMKL QADELLGYID YLYTVADKDV
KSTEPILEAT IKSKNEVGNL IKNRMKSLLD SFSVLSGCIR QTQFLLLDAV SLHQLFQMAS
STYNWIIEKE VYIQLLIMDD LKEEEFSKII EGDASANQGL IQRLEIVKNR FSDLEEQMST
AAEQVSKFTN RLLPYY
//
