ID A0A095TXP4_9FLAO Unreviewed; 380 AA.
AC A0A095TXP4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Cystathionine gamma-synthase {ECO:0000313|EMBL:KGD67093.1};
GN ORFNames=LG45_12765 {ECO:0000313|EMBL:KGD67093.1};
OS Flavobacterium aquatile LMG 4008 = ATCC 11947.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1453498 {ECO:0000313|EMBL:KGD67093.1, ECO:0000313|Proteomes:UP000029554};
RN [1] {ECO:0000313|EMBL:KGD67093.1, ECO:0000313|Proteomes:UP000029554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 4008 {ECO:0000313|EMBL:KGD67093.1,
RC ECO:0000313|Proteomes:UP000029554};
RA Gale A.N., Pipes S.E., Newman J.D.;
RT "Whole Genome Shotgun of Flavobacterium aquatile LMG 4008.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGD67093.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JRHH01000005; KGD67093.1; -; Genomic_DNA.
DR RefSeq; WP_035127615.1; NZ_MUGQ01000010.1.
DR AlphaFoldDB; A0A095TXP4; -.
DR STRING; 1453498.LG45_12765; -.
DR eggNOG; COG0626; Bacteria.
DR OrthoDB; 9803729at2; -.
DR Proteomes; UP000029554; Unassembled WGS sequence.
DR GO; GO:0016846; F:carbon-sulfur lyase activity; IEA:UniProt.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11808:SF92; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000029554}.
FT MOD_RES 196
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 380 AA; 41879 MW; 992CD3F049F0EAE6 CRC64;
MKFNTKVIHG GQHHEKVTGA VMTPVFQTST YVQTSPGKPV GDYEYSRAAN PTRQALEDAL
ASIENGARGL AFASGLAATD CLLRMFKAGD EIIAMDDLYG GTYRLFTRLY KDSGIKFHFV
DMNDLEKFQS LINENTKLVW VETPTNPLMK LADIAEIAKI TKKHNLLFAV DNTFATPYLQ
KPLDLGADIV MHSATKYLGG HSDVIAGALI IKDKELGDEL HFKQFATGGT LGPMDSYLVL
RGIKTLHLRV QRHCENGMKV AQFLSNHPKV ATVYYPGLPS HPFHDIAKKQ MSDFGGMVSF
TFKSGKKEDA ISFLEKVKVF TLAESLGGVE SLANHPALMT HASIPEDKRL EVGITDDLVR
LSTGVEDIED LLADLEQAFK
//
