ID A0A095WT22_9ACTO Unreviewed; 522 AA.
AC A0A095WT22;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Transporter {ECO:0000313|EMBL:KGF00758.1};
GN ORFNames=HMPREF1627_03930 {ECO:0000313|EMBL:KGF00758.1};
OS Actinomyces sp. S6-Spd3.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=1284680 {ECO:0000313|EMBL:KGF00758.1, ECO:0000313|Proteomes:UP000029604};
RN [1] {ECO:0000313|EMBL:KGF00758.1, ECO:0000313|Proteomes:UP000029604}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S6-Spd3 {ECO:0000313|EMBL:KGF00758.1,
RC ECO:0000313|Proteomes:UP000029604};
RA McCorrison J., Sanka R., Torralba M., Gillis M., Haft D.H., Methe B.,
RA Sutton G., Nelson K.E.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC {ECO:0000256|ARBA:ARBA00009854}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGF00758.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JRMV01000274; KGF00758.1; -; Genomic_DNA.
DR RefSeq; WP_034501239.1; NZ_JRMV01000274.1.
DR AlphaFoldDB; A0A095WT22; -.
DR PATRIC; fig|1284680.3.peg.522; -.
DR eggNOG; COG2985; Bacteria.
DR Proteomes; UP000029604; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR006512; YidE_YbjL.
DR NCBIfam; TIGR01625; YidE_YbjL_dupl; 1.
DR PANTHER; PTHR30445:SF3; TRANSPORT PROTEIN YIDE-RELATED; 1.
DR PANTHER; PTHR30445; UNCHARACTERIZED; 1.
DR Pfam; PF06826; Asp-Al_Ex; 2.
DR Pfam; PF02080; TrkA_C; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51202; RCK_C; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029604};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 254..338
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 522 AA; 54128 MW; 9F3D9EB085AC72BA CRC64;
MAQFLAQNHL LTLFLVVGLG AILGAIRVGP FRFGAAGALF VGLLVSAYSP EAGHGTAIIQ
QIGLAFFVYT VGIAAGSTFF ADLRRQSSLL GSATIICVVG AIIAWAGGHF LGLGKGLVTG
LYTGALTAAP ALDAATRVSG SGDAAVGYAF GYPIGVIVGI VVVTMTVTRK WIGEKDTPSL
AGAGLDAVTV RVERAVATRK IPAWREGRVR MSYLQREGRT RVLIPGEELR RGDLVVLVGG
SSAIAEVVEQ LGVQTEAHLA DDRSDVAFER IVVSSPDVAG RSIAELNMAT RFGAAITRVR
RGDLDLLASD DLKLNLGDHA AVVVPQEELD NVQSFLGDSE RRVSEVDGMA FGIGMVLGMA
LGAIPFPMFG GATFQLGSAA GPLIVGMLLG ALRRTGPLVW TLPASANITI RSIGLMLFLA
ALGLNAGPAF VELLASPQGW KAALLALIIV AACCVAQAIA GRFLGLSAPR SAGAVAGFLG
QPAVLQAADA RVADERIEAA YATLFAFAII VKIFLVPFIW TL
//
