ID A0A095Z218_9ACTO Unreviewed; 658 AA.
AC A0A095Z218;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Succinate dehydrogenase {ECO:0000313|EMBL:KGF02539.1};
DE EC=1.3.5.1 {ECO:0000313|EMBL:KGF02539.1};
GN Name=sdhA {ECO:0000313|EMBL:KGF02539.1};
GN ORFNames=HMPREF1628_01215 {ECO:0000313|EMBL:KGF02539.1};
OS Actinomyces sp. S4-C9.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=1219581 {ECO:0000313|EMBL:KGF02539.1, ECO:0000313|Proteomes:UP000035029};
RN [1] {ECO:0000313|EMBL:KGF02539.1, ECO:0000313|Proteomes:UP000035029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S4-C9 {ECO:0000313|EMBL:KGF02539.1,
RC ECO:0000313|Proteomes:UP000035029};
RA McCorrison J., Sanka R., Torralba M., Gillis M., Haft D.H., Methe B.,
RA Sutton G., Nelson K.E.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGF02539.1}.
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DR EMBL; JRMU01000002; KGF02539.1; -; Genomic_DNA.
DR RefSeq; WP_034506866.1; NZ_JRMU01000002.1.
DR AlphaFoldDB; A0A095Z218; -.
DR eggNOG; COG1053; Bacteria.
DR Proteomes; UP000035029; Unassembled WGS sequence.
DR GO; GO:0102040; F:fumarate reductase (menaquinone); IEA:UniProtKB-EC.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR GO; GO:0008177; F:succinate dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:KGF02539.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000035029}.
FT DOMAIN 51..461
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 523..657
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 346
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 658 AA; 73304 MW; 473FB8137C691D63 CRC64;
MTDQLIHGLY REGEKIADTK APLDVPLAQC WETRKFNAKL VNPANRRKLK VIIVGTGLAG
GAAAASLGEM GYHVDAFFYQ DSARRAHSIA AQGGINAAKN YRNDNDSVFR LFYDTVKGGD
YRARETNVYR LAEVSANIID QCVAQGVPFA REYGGLLDNR SFGGVQVSRT FYARGQTGQQ
LLIGAYQALE RQVEAGTVVE HRRHEMVELI VSDGRARGIV ARNMATGELE TYTADAVVLA
TGGYGNVFFL STNAMGCNGT AVWRAHRKGA YFGNPCYTQI HPTCIPQHGD QQSKLTLMSE
SLRNDGRIWV PKKAEDCKKD PRDIPEEDRD YYLERIYPSF GNLVPRDIAS RQAKNMCDDG
RGVGPEINGV ARGVYLDFAE AIERMGKDAV SAKYGNLFDM YERITGDNPY EVPMRIYPAV
HYTMGGLWVD YDLQSNLPGL FVAGEANFSD HGANRLGASA LMQGLSDGYF VLPNTINDYL
AGAFGFDKLD ENSPAVQEAL DSTQARIDKL MSIDGNRSVD SFHKELGHIM WEYCGMERNE
EGLKKAIGMI RELREEFYNN VRIPGKTKGE MNQSLEKAGR VADFLELGEL MCIDALHREE
SCGGHFRAEH QTPEGEALRH DDKFTYVAAW EFGADGVPTL HKEDLIYNNI ELKQRSYK
//
