ID A0A095ZDF1_9BURK Unreviewed; 340 AA.
AC A0A095ZDF1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase {ECO:0000313|EMBL:KGF32401.1};
DE EC=2.1.1.14 {ECO:0000313|EMBL:KGF32401.1};
GN ORFNames=HMPREF2130_00910 {ECO:0000313|EMBL:KGF32401.1};
OS Oligella urethralis DNF00040.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Oligella.
OX NCBI_TaxID=1401065 {ECO:0000313|EMBL:KGF32401.1, ECO:0000313|Proteomes:UP000029629};
RN [1] {ECO:0000313|EMBL:KGF32401.1, ECO:0000313|Proteomes:UP000029629}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DNF00040 {ECO:0000313|EMBL:KGF32401.1,
RC ECO:0000313|Proteomes:UP000029629};
RA McCorrison J., Sanka R., Torralba M., Gillis M., Haft D.H., Methe B.,
RA Sutton G., Nelson K.E.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the vitamin-B12 independent methionine synthase
CC family. {ECO:0000256|ARBA:ARBA00009553}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KGF32401.1}.
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DR EMBL; JRNI01000004; KGF32401.1; -; Genomic_DNA.
DR RefSeq; WP_018026351.1; NZ_JRNI01000004.1.
DR AlphaFoldDB; A0A095ZDF1; -.
DR GeneID; 61260855; -.
DR eggNOG; COG0620; Bacteria.
DR OrthoDB; 244285at2; -.
DR Proteomes; UP000029629; Unassembled WGS sequence.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR016456; Met_Synthase_cat.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR30519; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR PANTHER; PTHR30519:SF0; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR Pfam; PF01717; Meth_synt_2; 1.
DR PIRSF; PIRSF005632; Met_synth_catalytic_prd; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:KGF32401.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029629};
KW Transferase {ECO:0000313|EMBL:KGF32401.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 5..330
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 340 AA; 38202 MW; 8E9DEE6CCA6158D0 CRC64;
MKKLLPTSTA GSLPKPSWLA EPEKLWSPWK LAGDELAAAK RDALLLTLKE QEVAGIDIIS
DGEQTRQHFV TTFIEHLDGV DFEKRETVRI RDRYDASVPT VIGEVARSKP VFVEAAKFLR
QHTQQPIKWA LPGPMTMIDT LYDAHYQSRE KLAWEFAKIL NQEAKELEAA GVDIIQFDEP
AFNVFFDDVN DWGIATLERA IEGLKCETAV HICYGYGIKA NTDWKKTLGS EWRQYEEFFP
KLQQSTIDLI SLECHNSHVP MDLLELIRGK KVMVGAIDVA TNVIETPEEV AATLRKAMQF
VDAENLYPCT NCGMAPLSRE VANAKLRALS AGAAIVRNEL
//
