ID   A0A096LY26_POEFO        Unreviewed;       959 AA.
AC   A0A096LY26;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=Sorting nexin 19 {ECO:0000313|Ensembl:ENSPFOP00000024067.1};
GN   Name=SNX19 {ECO:0000313|Ensembl:ENSPFOP00000024067.1};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000024067.1, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000024067.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
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DR   EMBL; AYCK01019863; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01019864; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01019865; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01019866; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01019867; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01019868; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01019869; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01019870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01019871; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A096LY26; -.
DR   Ensembl; ENSPFOT00000027167.1; ENSPFOP00000024067.1; ENSPFOG00000015996.2.
DR   GeneTree; ENSGT00950000182856; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   CDD; cd06893; PX_SNX19; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR003114; Phox_assoc.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR037909; SNX19_PX.
DR   InterPro; IPR013937; Sorting_nexin_C.
DR   PANTHER; PTHR22775; SORTING NEXIN; 1.
DR   PANTHER; PTHR22775:SF31; SORTING NEXIN-19; 1.
DR   Pfam; PF08628; Nexin_C; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF02194; PXA; 1.
DR   SMART; SM00312; PX; 1.
DR   SMART; SM00313; PXA; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
DR   PROSITE; PS51207; PXA; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          72..248
FT                   /note="PXA"
FT                   /evidence="ECO:0000259|PROSITE:PS51207"
FT   DOMAIN          506..636
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          664..698
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        678..696
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   959 AA;  106951 MW;  3E4CB0A62CBB402C CRC64;
     MGQRSLMGIG VLLAWLLLFH LLVNIWLLCV FTSLLLVLGG WFGSQAILES NSLVHLERFI
     SLEQVQSSAE DEEHLDQEIH NTVRKIIRDF VISWYSTVST ESGFELEVQE AMISMAMKLK
     QRAKHIDRKE LTQKVLNLVG GHLQDYLTAK ELAKEKQHSE NEQLWKAYSS IATPHVAMSD
     YSAEINYIRA VVALLLHVLV PSPHLETNTG RFVVGELITS NVFLPLVAKL SDPDWLNLLI
     IEILCKSSTR LDSVASKLET CSLPLPAAES ETPTLQCVTQ ANSESLQQGA EMELTDDTEA
     ALPELHAYDA TDTEEVKFPQ TFSGEEEASR PFLRCYLRGR KSNPFYQETD SDPDSPLADY
     KPTSTDSLIM IGQVDTLYNR SKSYITTAED NSSIDLEEVS PSPVDGSYPK VLLNSVLVDS
     PNDGCLSSLR DTEITCSTNS LQDLKRENSS PAASQSRELV LGVEPTGLGN PSELIMASPL
     QGCSPVSTFS FEPLSSPEGP IIIQNLRITG TITAKEHRGT GSHPYTLYTI KYETSIGSEN
     PNPIQPVAYH MVNRRYSEFL NLQTRLEEKS ELRKFIKGVK GPKKVFPDMP FGNMDSDKIE
     ARKGLLETFL KQLCSISEIA NSEEMQEFLA LNTDARIAFV KKPFIVSRID KIVVNAIVGT
     LKTAFPHSEP QSPTEDTESE VDGGKMGTDK KNRSSRLKLS SKGVPFMNGS EIRPPVSFVW
     DQTSTVRELC NHSSVIHFCL KKTKLAFVGS STTSPDALSE SVPKSAIYEI LSGGSWQQPT
     YSDSAGEMSQ AKVALNILCL LMKEQWSWLC SKNIQRTVRL LFGTLINRWL DVSVANLTCT
     KYWVVYLQVI QEAVWPGGAL PAAPPPHRSQ QQKDSSKQQA LDGLMKLLPD LISDMLGSDK
     YRLSWQTALD SFQDPYINRH LVYCIFDLLL DFLVPELPEE DFQRSLLQTL AKNPEKMLT
//