ID A0A096M0L4_POEFO Unreviewed; 1031 AA.
AC A0A096M0L4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Integrin subunit alpha 9 {ECO:0000313|Ensembl:ENSPFOP00000024955.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000024955.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000024955.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
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DR EMBL; AYCK01002109; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096M0L4; -.
DR Ensembl; ENSPFOT00000029991.1; ENSPFOP00000024955.1; ENSPFOG00000024558.1.
DR GeneTree; ENSGT00940000156503; -.
DR OMA; MMRKGMA; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR Gene3D; 2.60.40.1530; ntegrin, alpha v. Chain A, domain 4; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR018184; Integrin_alpha_C_CS.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR048285; Integrin_alpha_Ig-like_2.
DR InterPro; IPR048286; Integrin_alpha_Ig-like_3.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF69; INTEGRIN ALPHA-9; 1.
DR Pfam; PF01839; FG-GAP; 2.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR Pfam; PF20805; Integrin_A_Ig_2; 1.
DR Pfam; PF20806; Integrin_A_Ig_3; 1.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 5.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 3.
DR PROSITE; PS51470; FG_GAP; 5.
DR PROSITE; PS00242; INTEGRIN_ALPHA; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003762};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003762};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU003762}.
FT TRANSMEM 974..998
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT REPEAT 33..98
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 236..290
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 291..350
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 352..409
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 414..475
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 460..620
FT /note="Integrin alpha first immunoglubulin-like"
FT /evidence="ECO:0000259|Pfam:PF08441"
FT DOMAIN 622..758
FT /note="Integrin alpha second immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20805"
FT DOMAIN 767..941
FT /note="Integrin alpha third immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20806"
SQ SEQUENCE 1031 AA; 114536 MW; 4C3017FFA411FE63 CRC64;
TTRKGMAPPL KHRTDVQQSF YVFLSISLAC SYNIDLEHPL VFQGPSSSFF GYSVLEHFHD
NTRWLIVGAP KANSTYSSSV RSPGAVFKCR VHSNPERRCT EMDLGRGNKP RESCGKTCQG
DRDDEWMGVS LARQDRASGK ILACAHRWKN VYYDSEHILP HGYCSIIPPT LQGRTMPLIP
CYEADYKQKY GEEHGSCQAG IAGVFTEELV VMGAPGSYYW TGTVKVYNMT SDTFYSPNKD
SIDSHRYSYL GYAVTAGHFS SPNAIDVAAG APQHNGVGKV YIFKLEAGSL VKNFQASGKM
MGSYFGSSLC AVDLNQDGLS DLLVGAPMHS QLRDEGQVSV YLSRGNGVME ENGVLTGDSA
FNAHFGESIA AIGDIDDDGY QDVAIGAPKE DDYGGAVYIY HGDATGITRK YSMKLSGRSV
SPGLQMFGQS ISGKVDMDGN GYADVTIGAF MADSVVLLRS RPVITVDVSI FLPVSINISV
PQCHEGHQNL NCFNITVCMH FRGREVPGEI ELLYNLTADV DKRQKSQPSR IYFTHTGSQI
SQMNQQLSLE INREKCQRYT AYVKKEVKDV FTAITFEVAY SLGKHVTTGQ QDRELPALTP
VLRWRKGNKI AVKNETWFEK NCLSDDCAAD LRLHGKLLLS GPHLALGAVR NVSLNVTISN
SGDDAYDTNI YFNFSREVLY INFWQKEEKG ISCGLVDLDF LKCSVGFPFM RAQTKYHFAV
IFDTTQVSGE NDTLQFLVQA KSANPEHKLS DNSLDLSISL IHETDTTITG VVTPGSFSYG
NSIDASHFIQ LEDMKCNFQP LNLTFQAINK GPSRLPGSTV DIRIPNRLAG NGPDMFHVVE
TQVSDGRGNC TPHRNLMPCT IPQDKENIFH SIFSFFTKSG RKVLDCDRPG RACMVISCSL
GPQLKDEALN IDLKLLLNTE ILKIDSSSVI QFVTRGSVQV NHRAIEVPNG LPEDIKIFHL
VFEALHSQEP RGYVVGWIIA ISLLVGILIF LLLAVLLWKM GFFRRHYREI IEAEKNRKDS
DESWDWMDKD H
//
