ID A0A096M4R2_POEFO Unreviewed; 580 AA.
AC A0A096M4R2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Receptor-type tyrosine-protein phosphatase-like N {ECO:0000313|Ensembl:ENSPFOP00000026403.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000026403.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000026403.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AYCK01019506; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01019507; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096M4R2; -.
DR STRING; 48698.ENSPFOP00000026403; -.
DR Ensembl; ENSPFOT00000029322.1; ENSPFOP00000026403.1; ENSPFOG00000024461.1.
DR eggNOG; KOG0793; Eukaryota.
DR GeneTree; ENSGT00940000170921; -.
DR OMA; CRFSPVC; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030141; C:secretory granule; IEA:InterPro.
DR Gene3D; 3.30.70.2470; Protein-tyrosine phosphatase receptor IA-2 ectodomain; 1.
DR InterPro; IPR033522; IA-2/IA-2_beta.
DR InterPro; IPR021613; Receptor_IA-2_dom.
DR InterPro; IPR038112; Receptor_IA-2_ectodomain_sf.
DR InterPro; IPR029403; RESP18_dom.
DR PANTHER; PTHR46106; IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C; 1.
DR PANTHER; PTHR46106:SF1; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE-LIKE N; 1.
DR Pfam; PF11548; Receptor_IA-2; 1.
DR Pfam; PF14948; RESP18; 1.
DR SMART; SM01305; RESP18; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..580
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001927588"
FT TRANSMEM 518..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 56..116
FT /note="RESP18"
FT /evidence="ECO:0000259|Pfam:PF14948"
FT DOMAIN 410..498
FT /note="Protein-tyrosine phosphatase receptor IA-2
FT ectodomain"
FT /evidence="ECO:0000259|Pfam:PF11548"
FT REGION 103..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 580 AA; 64170 MW; C3E76101809338D9 CRC64;
MQHLKPWRAL LLLAVLYQPA VSEKYGCLFE RKLCTRDQFC SDDGLFGQCR SSKQDQIQYQ
VTVPVLKRMQ EVLKQLMLQG LSWQDDITQY ILSKELKRVP HTTALSKPIS SSTSSHSSHS
KQHISHQPNS KSGSTSSGSK YVDYMYVEPP QSPLRMQTAP LDPYAYYQHR YQDEVERSLL
NGGGGYVRPS SRSQGSQREQ ERDRQLLQEV LSLYLASAQP SYRHRGSAPI PPAGLPYYED
LEIPVDYVED YTLEERLGTA GRQPNIQNKK APQESAPLVA NNDGLLQRMS GVLQKYNIDP
RELSQEQLYK LALILQLLQG QDKTDPNEKD LIALKEMQLL QKESVSKPDK AAPVPGPRDA
PAASSAIVPD KALPKSPSIP TSASKPPQAA PAEVEKSFKE PLVEGMEGKE QYGYIVTNQS
PLSLYDGVKL LQLLAEKIHL TTSSFINISV VGQALTFRIR QNEHNMTAAE VAAKAESEKN
FLESETGLKI VQTGVGERTN ARGLPQVIRI PPGSSGTVIT LVSMAVVGGV LVLAMGIACF
RHYGHQVANG KLGLGPEGGA ETHFDYQVRL QRKCKPSRGI
//
