ID A0A096MDL3_POEFO Unreviewed; 1065 AA.
AC A0A096MDL3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Par-3 family cell polarity regulator beta {ECO:0000313|Ensembl:ENSPFOP00000029504.1};
OS Poecilia formosa (Amazon molly) (Limia formosa).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000029504.1, ECO:0000313|Proteomes:UP000028760};
RN [1] {ECO:0000313|Proteomes:UP000028760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA Schartl M., Warren W.;
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPFOP00000029504.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endomembrane system
CC {ECO:0000256|ARBA:ARBA00004308}.
CC -!- SIMILARITY: Belongs to the PAR3 family.
CC {ECO:0000256|ARBA:ARBA00005358}.
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DR EMBL; AYCK01010667; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01010668; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01010669; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01010670; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AYCK01010671; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A096MDL3; -.
DR Ensembl; ENSPFOT00000024114.1; ENSPFOP00000029504.1; ENSPFOG00000003029.2.
DR GeneTree; ENSGT00950000183214; -.
DR Proteomes; UP000028760; Unassembled WGS sequence.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
DR CDD; cd00992; PDZ_signaling; 2.
DR Gene3D; 2.30.42.10; -; 3.
DR InterPro; IPR021922; Par3/HAL_N.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR16484:SF4; PARTITIONING DEFECTIVE 3 HOMOLOG B; 1.
DR PANTHER; PTHR16484; PARTITIONING DEFECTIVE 3 RELATED; 1.
DR Pfam; PF12053; Par3_HAL_N_term; 1.
DR Pfam; PF00595; PDZ; 2.
DR SMART; SM00228; PDZ; 3.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR PROSITE; PS50106; PDZ; 2.
PE 3: Inferred from homology;
KW Cell junction {ECO:0000256|ARBA:ARBA00022427};
KW Reference proteome {ECO:0000313|Proteomes:UP000028760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427}.
FT DOMAIN 419..504
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 534..606
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 79..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 815..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 900..1027
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..168
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..405
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 845..878
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 900..941
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1065 AA; 117319 MW; E87D2E520CC88492 CRC64;
MKVTVTFGDT SVVVPCKAGW TVRELIEQAT RRYRRIVEQE HGEVPVNIHH LEYTDGGILD
IDDLLSDLVE DREKLVAVFD DDQRSGTESP RDSISNGYSS DGASPEAMQY FPHLEYEDLS
RGEIEVNEAV LKANTPLLVR SSSDSVLAPS HETTPPPSPP PDDQSLKPPP EPEINNVLKG
ALERLNTENP PPKTMNQINF STLTRTVEFP GDRGPLGIHV VPYCSSLSGR PLGLHIKGIE
ENSRSKRDNL FKEDECIVHI NDTPLQDKTF AQSQEVFRQA MSSPTVRLEV VPVGSKPRYE
KTLIGQLFTG DGKDSPIKAM SPKVLRAPVE TLAETKLTQK VELKQPDPRP KTPEPAPQST
PPVQPQYGSL ERASPTPPAQ TASSSPPPRT RSQSPLANKS PAAPGVSNLA NKKGGKRVKI
DLRKGTEGLG FTVVTRDTAV HGPGPILVKN ILQRGAAIKD GRLQPGDRIL EVNGVDMTGR
TQEELVGMLR STKQGEVVSV LVSRQEDVFL PRELKGEERS SQAMEEGKEQ LMYEIPLNET
GSAGLGVSLK GNRSRETGED LGIFIKSIIH GGAAHKDGRL NVNDQLIAVN GESLLGRSNQ
AAMDTLIRSM SSEGNMRGTI QLVVLRSSRQ PRSGDKRLSR RLIATGSAAD KARLRHVWHL
LNYNLMPNSH WELTLPQENP KIFKGHNTNS LNGDEQRPAT ISTLLQVASS SHMEKHSAPS
LEKDNVPRNR TSKSMDLVAD ESNVGSLVGQ RNVPPFRGAL GPTLGLVKSS SLESLQTAVS
EAQQSRQQAQ VPFHRPRPHV VRGRACNQSF RIAIDKSYDG PSEDDDDVSD DSSGHETPAS
SSSRQDLDAD DKSKKKTEDS VDEPEKKTKK KNYSEQRILK IEESVTKKCK QLPFFVSCRF
GKKKEDKSKD PAKGSKNRLE ALSEEELDRI PDSREGNEPR YADARSGYAT PDQASLPSME
DDDSDPNYAR INDFRQPPSP LSLSRTPSPA MPRGGPVQPQ ASFEDINGLY AKVNKSRPPT
PVNPDQTLDQ RIQGLRREYQ QARAAPAYEE LEAARRRVLE HDPNR
//
