ID   A0A096MIH5_POEFO        Unreviewed;       622 AA.
AC   A0A096MIH5;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Poecilia formosa (Amazon molly) (Limia formosa).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48698 {ECO:0000313|Ensembl:ENSPFOP00000031216.1, ECO:0000313|Proteomes:UP000028760};
RN   [1] {ECO:0000313|Proteomes:UP000028760}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000028760};
RA   Schartl M., Warren W.;
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPFOP00000031216.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AYCK01028375; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AYCK01028376; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A096MIH5; -.
DR   STRING; 48698.ENSPFOP00000031216; -.
DR   Ensembl; ENSPFOT00000030426.1; ENSPFOP00000031216.1; ENSPFOG00000023605.1.
DR   eggNOG; ENOG502SBIG; Eukaryota.
DR   GeneTree; ENSGT01100000263513; -.
DR   OMA; RTHGAVC; -.
DR   Proteomes; UP000028760; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000028760}.
FT   DOMAIN          84..216
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   622 AA;  71649 MW;  E60D9918DA06A763 CRC64;
     VGQYQPDFKA SLKKKFQSLS EGISEPGNQT SLNQIYPELH ITEELTTEVK QEHEVRRIET
     ASRKQETAIR REDIFKPGRG QPIRTVMTMG VAGIGKTLLT QKFTLDWAEG KTNQNIDFIF
     PFTFRELNNL EEEKFSLLGL IHKLFSKTKE ISSFEGLQVL FIFVGLDESR LPLDFENNKI
     LTDATESSSL DVLLTNLIGG KLLPSALLWI TTRPAAANQI PADFVDLVTE VRGFTDPQKE
     EYFRKRFRDD EEKASRIISH IQKSKTLHIM CHIPVFCWIT AEVLEEMMKT REEGELPKTL
     TEMYIEFLLF QLTIKEEKYR RKPEEDPENR KLIETLGSLA FDQLQEGNLI FYDKDLKRCG
     IDIKDAALFS EVVTEMFKEK KGLGNISIYS FVHLSIQEFL AAVYMLHCFT SRRSEVIKTF
     LGEEYDETSL DEFMKKVMYK SLSSKNGHLD LFVRFLHGLT VESNQRLLED LLGIITNLKE
     MNTDRISPDR SINIFYCLVE MNDVSFYQEI QRLLDSGKQL SVTDCSALTF MLQMSEVLDE
     LDLEKYNTSE SGRQKIFNIL KFCFKFRLYS CSLSETSWTS LFSALKSNPT HLTGLELRDS
     NLGDSAVKEL CGFLQTQGCK LQ
//