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Database: UniProt
Entry: A0A096NHJ8_PAPAN
LinkDB: A0A096NHJ8_PAPAN
Original site: A0A096NHJ8_PAPAN 
ID   A0A096NHJ8_PAPAN        Unreviewed;      2672 AA.
AC   A0A096NHJ8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   30-AUG-2017, entry version 24.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor type 3 {ECO:0000313|Ensembl:ENSPANP00000012446};
GN   Name=ITPR3 {ECO:0000313|Ensembl:ENSPANP00000012446};
OS   Papio anubis (Olive baboon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Papio.
OX   NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000012446, ECO:0000313|Proteomes:UP000028761};
RN   [1] {ECO:0000313|Ensembl:ENSPANP00000012446, ECO:0000313|Proteomes:UP000028761}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A.,
RA   Aqrawi P.A., Arias F.A., Attaway T.A., Awwad R.A., Babu C.B.,
RA   Bandaranaike D.B., Battles P.B., Bell A.B., Beltran B.B.,
RA   Berhane-Mersha D.B., Bess C.B., Bickham C.B., Bolden T.B.,
RA   Carter K.C., Chau D.C., Chavez A.C., Clerc-Blankenburg K.C.,
RA   Coyle M.C., Dao M.D., Davila M.L.D., Davy-Carroll L.D., Denson S.D.,
RA   Dinh H.D., Fernandez S.F., Fernando P.F., Forbes L.F., Francis C.F.,
RA   Francisco L.F., Fu Q.F., Garcia-Iii R.G., Garrett T.G., Gross S.G.,
RA   Gubbala S.G., Hirani K.H., Hogues M.H., Hollins B.H., Jackson L.J.,
RA   Javaid M.J., Jhangiani S.J., Johnson A.J., Johnson B.J., Jones J.J.,
RA   Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K., Kovar C.K.,
RA   Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA   Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA   Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA   Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA   Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA   Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P.,
RA   Perez Y.P., Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q.,
RA   Rouhana J.R., Ruiz M.R., Ruiz S.-J.R., Saada N.S., Santibanez J.S.,
RA   Scheel M.S., Schneider B.S., Simmons D.S., Sisson I.S., Tang L.-Y.T.,
RA   Thornton R.T., Tisius J.T., Toledanes G.T., Trejos Z.T., Usmani K.U.,
RA   Varghese R.V., Vattathil S.V., Vee V.V., Walker D.W.,
RA   Weissenberger G.W., White C.W., Williams A.W., Woodworth J.W.,
RA   Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N., Nazareth L.N.,
RA   Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT   "Whole Genome Assembly of Papio anubis.";
RL   Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPANP00000012446}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSPANP00000012446}.
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DR   EMBL; AHZZ01193105; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHZZ01193106; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSPANT00000026212; ENSPANP00000012446; ENSPANG00000017411.
DR   GeneTree; ENSGT00760000119152; -.
DR   OMA; VVVFYND; -.
DR   OrthoDB; EOG091G00T2; -.
DR   Proteomes; UP000028761; Chromosome 4.
DR   ExpressionAtlas; A0A096NHJ8; baseline.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:Ensembl.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:Ensembl.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0043235; C:receptor complex; IEA:Ensembl.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:Ensembl.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:Ensembl.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0050913; P:sensory perception of bitter taste; IEA:Ensembl.
DR   GO; GO:0050916; P:sensory perception of sweet taste; IEA:Ensembl.
DR   GO; GO:0050917; P:sensory perception of umami taste; IEA:Ensembl.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt-bd.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028761};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028761};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2202   2227       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2239   2257       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2269   2289       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2325   2350       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2370   2392       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2499   2522       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      113    173       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      174    224       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      232    288       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      379    435       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     2630   2657       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2672 AA;  303959 MW;  0A3FCBCB6A37878E CRC64;
     MSEMSSFLHI GDIVSLYAEG SVNGFISTLG LVDDRCVVEP AAGDLDNPPK KFRDCLFKVC
     PMNRYSAQKQ YWKAKQTKQD KEKIADVVLL QKLQHAAQME QKQNDTENKK VHGDVVKYGS
     VIQLLHMKSN KYLTVNKRLP ALLEKNAMRV TLDATGNEGS WLFIQPFWKL RSNGDNVVVG
     DKVILNPVNA GQPLHASNYE LSDNAGCKEV NSVNCNTSWK INLFMQFRDH LEEVLKGGDV
     VRLFHAEQEK FLTCDEYKGK LQVFLRTTLR QSATSATSSN ALWEVEVVHH DPLPVEELGT
     GMACTASSTW TTGNYLAAEE NPSYKGDALD PKATGMGAQG RAGRRNAGEK IKYRLVAVPH
     GNDIASLFEL DPTTLQKTDS FVPRNSYVRL RHLCTNTWIQ STNVPIDIEE ERPIRLMLGT
     CPTKEDKEAF AIVSVPVSEI RDLDFANDAS SMLASAVEKL NEGFISQNDR RFVIQLLEDL
     VFFVSDVPNN GQNVLDIMVT KPNRERQKLM REQNILKQIF GILKAPFREK GGEGPLVRLE
     ELSDQKNAPY QHMFRLCYRV LRHSQEDYRK NQEHIAKQFG MMQSQIGYDI LAEDTITALL
     HNNRKLLEKH ITKTEVETFV SLVRKNREPR FLDYLSDLCV SNHIAIPVTQ ELICKCVLDP
     KNSDILIQTE LRPVKEMAQS HEYLSIEYSD EEVWLTWTDK NNEHHEKSVR QLAQEARAGN
     AHDENVLSYY RYQLKLFARM CLDRQYLAID EISQQLGVDL IFLCMADEML PFDLRASFCH
     LMLHVHVDRD PQELVTPVKF ARLWTEIPTA ITIKDYDSNL NASRDDKKNK FANTMEFVED
     YLNNVVSEAV PFANEEKNKL TFEVVSLAHN LIYFGFYSFS ELLRLTRTLL GIIDCVQGPP
     AMLQAYEDPG GKNVRRSIQG VGHMMSTMVL SRKQSVFGAP SLPAGASAAE PLDRSKFEEN
     EDIVVMETKL KILEILQFIL NVRLDYRISY LLSVFKKEFV EVFPMQDSGA DGTAPAFDST
     TANMNLDRIG EQAEAMFGVG KTSSMLEVDD EGGRMFLRVL IHLTMHDYAP LVSGALQLLF
     KHFSQRQEAM HTFKQVQLLI SAQDVENYKV IKSELDRLRT MVEKSELWVD KKGSGKGEEV
     EAGAAKDKKE RPTDEEGFLH PPGEKSSENY QIVKGILERL NKMCGVGEQM RKKQQRLLKN
     MDAHKVMLDL LQIPYDKGDA KMMEILRYTH QFLQKFCAGN PGNQALLHKH LHLFLTPGLL
     EAETMQHIFL NNYQLCSEIS EPVLQHFVHL LATHGRHVQY LDFLHTVIKA EGKYVKKCQD
     MIMTELTNAG DDVVVFYNDK ASLAHLLDMM KAARDGVEDH SPLMYHISLV DLLAACAEGK
     NVYTEIKCTS LLPLEDVVSV VTHEDCITEV KMAYVNFVNH CYVDTEVEMK EIYTSNHIWT
     LFENFTLDMA RVCSKREKRV ADPALEKYVL SVVLDTINAF FSSPFSENST SLQTHQTIVV
     QLLQSTTRLL ECPWLQQQHK GSVEACIRTL AMVAKGRAIS LPMDLDAHIS AMLSSGASCA
     AAAQRNASSY KATTRAFPRV TPTANQWDYK NIIEKLQDII TALEERLKPL VQAELSVLVD
     VLHWPELLFL EGSEAYQRCE SGGFLSKLIQ HTKDLMESEE KLCIKVLRTL QQMLLKKTKY
     GDRGNQLRKM LLQNYLQNRK STSRGDLPDP MGTGLDPDWS AIAATQCRLD KEGATKLVCD
     LITSTKNEKI FQESIGLAIR LLDGGNTEIQ KSFHNLMMSD KKSERFFKVL HDRMKRAQQE
     TKSTVAVNMN DLGSQPHEDR EPVDPTTKGR VASFSIPGSS SRYSLGPSLR RGHEVSERVQ
     SNEMGTSVLI MQPILRFLQL LCENHNRDLQ NFLRCQNNKT NYNLVCETLQ FLDIMCGSTT
     GGLGLLGLYI NEDNVGLVIQ TLETLTEYCQ GPCHENQTCI VTHESNGIDI ITALILNDIS
     PLCKYRMDLV LQLKDNASKL LLALMESRHD SENAERILIS LRPQELVDVI KKAYLQEEER
     ENSEVSPREV GHNIYILALQ LSRHNKQLQH LLKPVKRIQE EEAEGISSML SLNNKQLSQM
     LKSSVPAQEE EEDPLAYYEN HTSQIEIVRQ DRSMEQIVFP VPGICQFLTE ETKHRLFTTT
     EQDEQGSKVS DFFDQSSFLH NEMEWQRKLR SMPLIYWFSR RMTLWGSISF NLAVFINIII
     AFFYPYMEGA STGVLDSPLI SLLFWILICF SIAALFTKRY SIRPLIVALI LRSIYYLGIG
     PTLNILGALN LTNKIVFVVS FVGNRGTFIR GYKAMVMDME FLYHVGYILT SVLGLFAHEL
     FYSILLFDLI YREETLFNVI KSVTRNGRSI LLTALLALIL VYLFSIVGFL FLKDDFILEV
     DRLPNNHSTA SPLGMPHGAA AFVDTCSGDK MDCVSGVSVP EVLEEDGELD STERACDTLL
     MCIVTVMNHG LRNGGGVGDI LRKPSKDESL FPARVVYDLL FFFIVIIIVL NLIFGVIIDT
     FADLRSEKQK KEEILKTTCF ICGLERDKFD NKTVSFEEHI KLEHNMWNYL YFIVLVRVKN
     KTDYTGPESY VAQMIKNKNL DWFPRMRAMS LVSNEGEGEQ NEIRILQDKL NSTMKLVSHL
     TGQLNELKEQ MTEQRKRRQR LGFVDVQNCM SR
//
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