ID A0A096NSW2_PAPAN Unreviewed; 1510 AA.
AC A0A096NSW2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Myosin XVB {ECO:0008006|Google:ProtNLM};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000016133.3, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000016133.3, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000016133.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR Ensembl; ENSPANT00000025624.3; ENSPANP00000016133.3; ENSPANG00000020136.3.
DR eggNOG; KOG4229; Eukaryota.
DR GeneTree; ENSGT00930000151032; -.
DR HOGENOM; CLU_000192_14_0_1; -.
DR OMA; VIQCLSP; -.
DR Proteomes; UP000028761; Chromosome 17.
DR Bgee; ENSPANG00000020136; Expressed in ventromedial nucleus of hypothalamus and 52 other cell types or tissues.
DR ExpressionAtlas; A0A096NSW2; baseline.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR CDD; cd12068; SH3_MYO15B; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR035489; MYO15B_SH3.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR22692; MYOSIN VII, XV; 1.
DR PANTHER; PTHR22692:SF16; MYOSIN XVB; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF00784; MyTH4; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00139; MyTH4; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51016; MYTH4; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000028761};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 99..318
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 475..626
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1402..1463
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..219
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 722..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 886..952
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 973..1185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..745
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..910
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..951
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1019..1033
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1123..1138
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1166..1183
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1510 AA; 164849 MW; DF0DD83C147C271F CRC64;
MKEASGVGEG HSPMCPPHCR TPLGPAGEWP GATVQQPRQR APAALLQPDA AGAGRGRVSA
GAAVLGACPS ASEGILPGPP GRPAPQPPEY PGCPDMAVPA TDHTFLQKSH YHHGDHPSYA
KPRLPLPVFT VQHYAGTVTY QVHKFLNRNR DQLDPAVVEM LGQSQLQLVG SLFQEAEPQS
RGGRGRPTLA SRFQQALGDL IARLGRSHVY FIQCLNPNPG KLPGLFDVGH VTEQLHQAAI
LEAVGTRSAN FPVRVPFGAF LARFQALGSE GQEDLSDREK CGTILSQVLG AKSPLCHLGA
TKVLLQEQGW QQLEELRDQQ RSQALVNLHR SFHTCISRQR VLPRMQARMR GFQARKRCLR
RRAALGQLNT MLLVAQPLLR RRQRLQLGHW QGWHSSERAL ERVPSMELGR LEIPAELAVM
LKTAEGHQDA LAGSITECLP PEVPARPSLT LPPDIDRFPF SSFVSIGFQE PSLPRPGQPL
VKPLTQLDGE NPQHALDINK VMLRLLGDGS LESWQRQTMG TYLVRQGQCQ PGLRNELFSQ
LVAQLWQNPD EQQSQRGWAL MAVLLSAFPP LPVLQKPLLK FVSDQAPRGM AALCQHKLLG
ALEQSQLAPG ATRAHPPTQL EWMAGWRRGR MALDVFTFSE ECYSAEVESW TTGEQLAGWI
LQSRGLEVPP RGWSVSLHSR DTWQDLAGCD FVLDLISQTE DLGDPAAPHS YPITPLGSTE
AIPLAPGIQA PSLPPGPPPG PAPTLPSRDH TGEVQRSGSL DGFLDQIFQP VMSSGLSDLE
QSWALSSRMK GGGAVGPTQQ GYPMVYPGMI QMPGYQPGMV PAPMPMMPAM GTVPAMPAVV
VPPQPPLPSL DAGQLAIQQQ NFINQQALIL AQQMTAQAMT LSLEQQTQQQ QRQRQARASE
AASQASPSAI ASKPRKPPTP LEKPQHDLES EGGCLRETSE EAEDRPCRPK SFQQKRNYFQ
KMGQPQITVR AVKPPAKVQI PQGEAQEEEE EEQEEQEVET RAVPSPPPPP IMKKPLKQGG
AKAAKEAEAE PVKETAAKGG GQGPAQGMGI VVRSSDPKPK RPQPSREIGN IIRMYQSRPG
PVPVPVQPSR PPKTFLKKID PKDEALAKLG INGAHSSPPM LSSSPGKGPP PAVAPRPKTP
LQLGPSSSIK EKQGPLLDLF GQKLPTAQTP PPPPAPPLPL PEEPGTLSAE RRCLTQPMED
QGVSTQLLAP SGSVCFSYTG KPWKLFLRKE VFYPRENLSH PYYLRLLCEQ ILRDTFSESC
IRISQDERRK MKDLLGDLEV DLDSLTTTED GVKKRIVVAA RDNWANYFSR FFPVSGESGS
DVQLLAVSHR GLRLLKVTQA SSLRPHQLKI LCSYSFAEVL GVECRGSSTL QLSLKSEQLV
LHTARARAIE ALVKLFLSEL KKDSGYVIAL RSYITDNCSL LSFHRGDLIK LLPVATLEPG
WQFGSAGGRS GLFPADIVQP AAAPDFSFSK EQRSGWHKGQ LSNGELGLAR WDRASEVRKM
AEGEPQARPA
//
