ID A0A096NXX4_PAPAN Unreviewed; 789 AA.
AC A0A096NXX4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Dipeptidyl peptidase like 10 {ECO:0000313|Ensembl:ENSPANP00000017930.3};
GN Name=DPP10 {ECO:0000313|Ensembl:ENSPANP00000017930.3};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000017930.3, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000017930.3, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000017930.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A096NXX4; -.
DR Ensembl; ENSPANT00000018673.3; ENSPANP00000017930.3; ENSPANG00000019222.3.
DR eggNOG; KOG2100; Eukaryota.
DR GeneTree; ENSGT00940000154657; -.
DR HOGENOM; CLU_006105_4_1_1; -.
DR OrthoDB; 2876738at2759; -.
DR Proteomes; UP000028761; Chromosome 10.
DR Bgee; ENSPANG00000019222; Expressed in olfactory bulb and 42 other cell types or tissues.
DR ExpressionAtlas; A0A096NXX4; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF21; INACTIVE DIPEPTIDYL PEPTIDASE 10; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028761};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 126..492
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 575..776
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 789 AA; 90150 MW; 5A7FB6FAA83E0495 CRC64;
MRKVESRGEG GREELGSNSP PQRNWKGIAI ALLVILVVCS LITMSVILLT PDELTNSSET
RLSLEDLFRK DFVLHDPEAR WINDTDVVYK SENGHVIKLN IETNATTLLL ENTTFVTFKA
SRHSVSPDLK YVLLAYDVKQ VFHYSYTASY VIYNIHTREV WELNPPEVED SVLQYAAWGV
QGQQLIYIFE NNIYYQPDIK SSSLRLTSSG KEEIIFNGIA DWLYEEELLH SHIAHWWSPD
GERLAFLMIN DSLVPTMVIP RFTGALYPKG KQYPYPKAGQ VNPTIKLYVV NLYGPTHTLE
LMPPDSFKSR EYYITMVKWV SNTKTVVRWL NRPQNISILT VCETTTGACS KKYEMTSDTW
LSKQNEEPVF SRDGSKFFMT VPVKQGGRGE FHHIAMFLIQ SKSEQITVRH LTSGNWEVIK
ILAYDETTQK IYFLSTESSP RGRQLYSAST EGLLNRQCIS CNFMKEQCTY FDASFSPMNQ
HFLLFCEGPR VPVVSLHSTG NPAKYFILES NSMLKEAILK KKIVKPEVKI LHIDDYELPL
QLSLPKDFMD RNQYALLLIM DEEPGGQLVT DKFHIDWDSV LIDMDNVIVA RFDGRGSGFQ
GLKILQEIHR RLGSVEVKDQ ITAVKFLLKL PYIDSKRLSI FGKGYGGYIA SMILKSDEKL
FKCGSVVAPI TDLKLYASAF SERYLGMPSK EESTYQAASV LHNIHGLKEE NILIIHGTAD
TKVHFQHSAE LIKHLIKAGV NYTMQVYPDE GHNVSEKSKY HLYSTILKFF SDCLKEEISV
LPQEPEEDE
//
