ID A0A096UQP3_WHEAT Unreviewed; 361 AA.
AC A0A096UQP3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=mannose-1-phosphate guanylyltransferase {ECO:0000256|ARBA:ARBA00012387};
DE EC=2.7.7.13 {ECO:0000256|ARBA:ARBA00012387};
GN ORFNames=CFC21_062155 {ECO:0000313|EMBL:KAF7054490.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4A02G094000.1};
RN [1] {ECO:0000313|EMBL:KAF7054490.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7054490.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4A02G094000.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4A02G094000.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS4A02G094000.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7054490.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7054490.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-mannose 1-phosphate + GTP + H(+) = diphosphate + GDP-
CC alpha-D-mannose; Xref=Rhea:RHEA:15229, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:37565, ChEBI:CHEBI:57527,
CC ChEBI:CHEBI:58409; EC=2.7.7.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001083};
CC -!- PATHWAY: Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose
CC biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP
CC route): step 1/1. {ECO:0000256|ARBA:ARBA00004823}.
CC -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC {ECO:0000256|ARBA:ARBA00007274}.
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DR EMBL; CM022222; KAF7054490.1; -; Genomic_DNA.
DR SMR; A0A096UQP3; -.
DR STRING; 4565.A0A096UQP3; -.
DR PaxDb; 4565-Traes_4AS_B59D0F85B-1; -.
DR EnsemblPlants; TraesCS4A02G094000.1; TraesCS4A02G094000.1; TraesCS4A02G094000.
DR EnsemblPlants; TraesCS4D02G211100.1; TraesCS4D02G211100.1; TraesCS4D02G211100.
DR Gramene; TraesCAD_scaffold_064439_01G000100.1; TraesCAD_scaffold_064439_01G000100.1; TraesCAD_scaffold_064439_01G000100.
DR Gramene; TraesCAD_scaffold_067995_01G000300.1; TraesCAD_scaffold_067995_01G000300.1; TraesCAD_scaffold_067995_01G000300.
DR Gramene; TraesCLE_scaffold_069661_01G000100.1; TraesCLE_scaffold_069661_01G000100.1; TraesCLE_scaffold_069661_01G000100.
DR Gramene; TraesCS4A02G094000.1; TraesCS4A02G094000.1; TraesCS4A02G094000.
DR Gramene; TraesCS4A03G0192700.1; TraesCS4A03G0192700.1.CDS; TraesCS4A03G0192700.
DR Gramene; TraesCS4D02G211100.1; TraesCS4D02G211100.1; TraesCS4D02G211100.
DR Gramene; TraesCS4D03G0516100.1; TraesCS4D03G0516100.1.CDS; TraesCS4D03G0516100.
DR Gramene; TraesKAR4A01G0063620.1; cds.TraesKAR4A01G0063620.1; TraesKAR4A01G0063620.
DR Gramene; TraesKAR4D01G0260810.1; cds.TraesKAR4D01G0260810.1; TraesKAR4D01G0260810.
DR Gramene; TraesPAR_scaffold_053050_01G000500.1; TraesPAR_scaffold_053050_01G000500.1; TraesPAR_scaffold_053050_01G000500.
DR Gramene; TraesRN4A0100194300.1; TraesRN4A0100194300.1; TraesRN4A0100194300.
DR Gramene; TraesRN4D0100534400.1; TraesRN4D0100534400.1; TraesRN4D0100534400.
DR Gramene; TraesROB_scaffold_070552_01G000100.1; TraesROB_scaffold_070552_01G000100.1; TraesROB_scaffold_070552_01G000100.
DR Gramene; TraesWEE_scaffold_062511_01G000100.1; TraesWEE_scaffold_062511_01G000100.1; TraesWEE_scaffold_062511_01G000100.
DR Gramene; TraesWEE_scaffold_096813_01G000100.1; TraesWEE_scaffold_096813_01G000100.1; TraesWEE_scaffold_096813_01G000100.
DR eggNOG; KOG1322; Eukaryota.
DR HOGENOM; CLU_029499_0_0_1; -.
DR OMA; MECAKET; -.
DR OrthoDB; 5486038at2759; -.
DR UniPathway; UPA00126; UER00930.
DR Proteomes; UP000019116; Chromosome 4A.
DR Proteomes; UP000019116; Chromosome 4D.
DR Proteomes; UP000815260; Chromosome 4D.
DR ExpressionAtlas; A0A096UQP3; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase (GTP) activity; IBA:GO_Central.
DR GO; GO:0009298; P:GDP-mannose biosynthetic process; IBA:GO_Central.
DR GO; GO:0006486; P:protein glycosylation; IBA:GO_Central.
DR CDD; cd06425; M1P_guanylylT_B_like_N; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR045233; GMPPB_N.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR22572:SF15; MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE BETA; 1.
DR PANTHER; PTHR22572; SUGAR-1-PHOSPHATE GUANYL TRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 2..233
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 361 AA; 39326 MW; CE20BD7F4C646410 CRC64;
MKALILVGGF GTRLRPLTLS VPKPLVDFAN KPMILHQIEA LKDVGVTEVV LAINYQPEVM
LNFLKDFESK LGIKITCSQE TEPMGTAGPL ALARDKLDDG SGEPFFVLNS DVISEYPFAE
LIEFHKSHGG EATIMVTKVD EPSKYGVVVT EEETGKVERF VEKPKVFVGN KINAGIYLLS
PSVLDRIELK PTSIEKEVFP RIAADKGLYA MVLPGFWMDI GQPRDYITGL RLYLESLRKR
APARLAAGAH VLGNVLVHET ATIGEGCLIG PDVAVGPGCV VEAGVRLSRC TVMRGARVKK
HACISGSIVG WHSTVGKWAR VENMTILGED VHVCDEVYSN GGVVLPHKEI KSSILKPEIV
M
//
