ID A0A097EK09_9SPHN Unreviewed; 399 AA.
AC A0A097EK09;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=4-hydroxytetrahydrobiopterin dehydratase {ECO:0000313|EMBL:AIT07897.1};
GN ORFNames=MC45_01015 {ECO:0000313|EMBL:AIT07897.1};
OS Sphingomonas taxi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1549858 {ECO:0000313|EMBL:AIT07897.1, ECO:0000313|Proteomes:UP000033200};
RN [1] {ECO:0000313|EMBL:AIT07897.1, ECO:0000313|Proteomes:UP000033200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 55669 {ECO:0000313|EMBL:AIT07897.1,
RC ECO:0000313|Proteomes:UP000033200};
RA Zhou Y., Ma T., Liu T.;
RT "Using Illumina technology Improving SMRT sequencing Genome Assembly by
RT RASTools.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP009571; AIT07897.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A097EK09; -.
DR STRING; 1549858.MC45_01015; -.
DR KEGG; stax:MC45_01015; -.
DR eggNOG; COG0523; Bacteria.
DR HOGENOM; CLU_017452_2_0_5; -.
DR Proteomes; UP000033200; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000033200}.
FT DOMAIN 253..369
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 399 AA; 44016 MW; F71ABE8DCA8DBF8A CRC64;
MTVLSGFLGA GKTTLLNHIL VNREGRRVAV IVNDMSEVNI DADLVRGGEA ALSRSEEALV
EMTNGCICCT LRDDLLAEVR TLAEAGRFDY LVIESTGISE PLPVATTFSF RDEDGVSLGD
VARLDTMVTV VDAVNLLADY SSQDFLADRG ESMGQDDTRS LVGLLVEQIE FADVVIVNKA
SSVSAEQLGV VTKLVASLNA DAVIVAADHS RIDLDLVLAT GLFDEEKASR HPLWAKELYG
YAHHQPETEE YGIESFVYRT RAPFDPAKFH AFLTDGGLDH VVRAKGHFWL ATRPDWVGEL
AVAGSQTETA RMGRWWASIP KHQWPDDGRF EEFVARHWDM IWGDRRQELV FIGIGMDEAR
IRTRLDACLV PAAAFTPALW SGLRDPFPGW GKRQPEAAE
//
