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Database: UniProt
Entry: A0A097SS13_9MOLU
LinkDB: A0A097SS13_9MOLU
Original site: A0A097SS13_9MOLU 
ID   A0A097SS13_9MOLU        Unreviewed;       457 AA.
AC   A0A097SS13;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   25-OCT-2017, entry version 20.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000313|EMBL:AIV03388.1};
GN   ORFNames=MGM1_0010 {ECO:0000313|EMBL:AIV03388.1};
OS   Candidatus Mycoplasma girerdii.
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=1318617 {ECO:0000313|EMBL:AIV03388.1, ECO:0000313|Proteomes:UP000030066};
RN   [1] {ECO:0000313|EMBL:AIV03388.1, ECO:0000313|Proteomes:UP000030066}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VCU_M1 {ECO:0000313|EMBL:AIV03388.1};
RX   PubMed=25337710;
RG   Vaginal Microbiome Consortium;
RA   Fettweis J.M., Serrano M.G., Huang B., Brooks J.P., Glascock A.L.,
RA   Sheth N.U., Strauss J.F.III., Jefferson K.K., Buck G.A.;
RT   "An emerging Mycoplasma associated with trichomoniasis, vaginal
RT   infection and disease.";
RL   PLoS ONE 9:E110943-E110943(2014).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP007711; AIV03388.1; -; Genomic_DNA.
DR   EnsemblBacteria; AIV03388; AIV03388; MGM1_0010.
DR   KEGG; mgj:MGM1_0010; -.
DR   KO; K02313; -.
DR   Proteomes; UP000030066; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000030066};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030066}.
FT   DOMAIN      144    295       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      367    436       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   457 AA;  52921 MW;  981E2DEF59E6172D CRC64;
     MNGSYDFNIV KINWSDIKEQ IKKSIKNSDI FNDFIKSVLV YGIDENNLIL SVKNELAKKT
     INNNYLSLFT SIVNKTLNAN FNLRFLTNEE IADWEENFKN KENKSVSFNK ANTNQRLSFN
     SYVVSQFNKN AYNALKSILD KKLVWNPIFI SSNVGLGKTH LLNAFANEYL RLNPNANVYY
     VTSDEFIREI YHSLQENSNK NINEVIDKYE SVDVLLIDDV QFLATKEKIS EIFFNIFNHN
     IAKGKIVIMS SDKHPDQMEN FHDRMKSRFS SGLCVEISKP SIESICQILE MKINEANLGF
     IFPKETILYI ARRNQSDIRK LNGYLNQILH YAFNNLSPGA IISINIVQTA TKITDIEEIK
     HRGFDIDPNI VIEQVCLAYG VDPKEVKSKS RLYQIANCRS ICMYVLRKKF DMKYEEIGKF
     FSNRNHSTVI TSIEKVKNKL ENDKVAADFI EKIYKNI
//
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