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Database: UniProt
Entry: A0A098GD48_TATMI
LinkDB: A0A098GD48_TATMI
Original site: A0A098GD48_TATMI 
ID   A0A098GD48_TATMI        Unreviewed;       450 AA.
AC   A0A098GD48;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-SEP-2017, entry version 26.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:CEG59376.1};
GN   ORFNames=LMI_0001 {ECO:0000313|EMBL:CEG59376.1};
OS   Tatlockia micdadei (Legionella micdadei).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Tatlockia.
OX   NCBI_TaxID=451 {ECO:0000313|EMBL:CEG59376.1, ECO:0000313|Proteomes:UP000032414};
RN   [1] {ECO:0000313|EMBL:CEG59376.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC33218 {ECO:0000313|EMBL:CEG59376.1};
RA   GOMEZ-VALERO Laura;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; LN614830; CEG59376.1; -; Genomic_DNA.
DR   RefSeq; WP_045097975.1; NZ_LNYM01000009.1.
DR   EnsemblBacteria; CEG59376; CEG59376; LMI_0001.
DR   KEGG; tmc:LMI_0001; -.
DR   PATRIC; fig|451.8.peg.973; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   Proteomes; UP000032414; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032414};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032414}.
FT   DOMAIN      147    349       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      358    427       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     155    162       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   450 AA;  51360 MW;  B870129FE3B17ED6 CRC64;
     MSEDVWKKCR ELLEEEYPPQ QFNTWLRPLQ AEVHDNGLVL LAPNRFVVDW VKRNFYTRLK
     ELISQIGGDA FSLLSISIGT KTAEPVSTDS QSIIAPINVP KPTPKKTADY KNSYLNKKFV
     FESFVEGNSN QLARAASWQV AERPGDAYNP LFIYGGVGLG KTHLMHAIGN AILKNDPEAK
     VLYLHSERFV ADMVKALQTN SINEFKRFYR SLNVLLIDDI QFFAGKDRSQ EEFFHTFNAL
     LEGQQQIILT SDRYPKEIEG MEERLKSRFG WGLTVAVEPP ELETRVAILI SKAEQSNIEL
     PYEVAFFIAK RIRSNVRELE GALRRVIANA HFTGKPITID FVQEALRDLL ALQDKLVTIE
     NIQKTVAEYY KVKVADLLSK RRSRSIARPR QMAMALAKEL TNHSLPEIGD HFGGRDHTTV
     LHACRKVKEL IQDDNDFAED YKNLMRTLSS
//
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