ID   A0A098TM63_9CYAN        Unreviewed;       779 AA.
AC   A0A098TM63;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DO97_14320 {ECO:0000313|EMBL:KGF71928.1};
OS   Neosynechococcus sphagnicola sy1.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Leptolyngbyales;
OC   Neosynechococcaceae; Neosynechococcus.
OX   NCBI_TaxID=1497020 {ECO:0000313|EMBL:KGF71928.1, ECO:0000313|Proteomes:UP000030170};
RN   [1] {ECO:0000313|EMBL:KGF71928.1, ECO:0000313|Proteomes:UP000030170}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CAUP A 1101 {ECO:0000313|EMBL:KGF71928.1,
RC   ECO:0000313|Proteomes:UP000030170};
RA   Dvorak P., Casamatta D., Hasler P., Poulickova A., Ondrej V., Sanges R.;
RT   "Evolution of Synechococcus.";
RL   Mol. Ecol. 0:0-0(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KGF71928.1}.
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DR   EMBL; JJML01000044; KGF71928.1; -; Genomic_DNA.
DR   RefSeq; WP_036535430.1; NZ_JJML01000044.1.
DR   AlphaFoldDB; A0A098TM63; -.
DR   STRING; 1497020.DO97_14320; -.
DR   Proteomes; UP000030170; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030170};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        23..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          345..397
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          395..436
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          470..522
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
SQ   SEQUENCE   779 AA;  88045 MW;  E949B111F7A3062A CRC64;
     MNLTQFFQPA TTLIHRLKYP QKFALISCVF ILPLGLVMYL LLSEIQTRIN FAQKEIVGNL
     YLRPLSQLSE KIFQYQFFSH RSLILHQPSQ VTTSRALAVT TDFRSLGILD QAFNDRLQTT
     ERLKRLEASW HQLAEIQRQQ NLSASIPAYQ DVLQNLDELR FQVGDQSNLI LDPDLDSYYL
     MDATLLKLPE IQKNLAEIHL ISQQAILRGR ILPSEQAKLM LLGVNLKQFR ANLKQKIAVA
     FANNPKGNLV PQLTEPLTLL TEDVGKLTEL LLPLDARQPL QLKQILAQAN QSLLQSFQFW
     NTAIDELDIL LQNRIDGFFR KQVFLTTFVL IILAIVCYLF VGFYLSVMQT ISGLSAAADR
     MINGNFSEEM ALESHDELTE VVQSFNNIAD ALREAEAKYR GIFENAVEGI FQTTQTGNYL
     IANPMLARIY GYDSAEELIT ALTDIEHQLY VDPHRRSEFT QLIAAQGKVQ GFESQVYCKD
     GSIIWISESV RAIQDPLGEV IGYEGTVEDI TQRKLAEAEI IQLTQRLKHE NLRMGAELEV
     SRQLQTMLLP SDAELEAVIG LEIAGFMEPA AEVGGDYYDV LQHEGKIRIG IGDVTGHGLE
     SGVVMLMAQT AVRTLLTHGE TDPTRFLNTV NTIIYENTQR MRSPKNMTLA LLNYEAGMLS
     LSGQHEEVII VRRDGRIEPI DTLDLGFPLG LESDITSFVA ETQIQLQSGD IAVLYTDGIT
     EAMNAQRQQY GLDRMYGILR RHCEDSASNI RQAIIEDLRE FIGDQKVFDD ITLLILKQR
//