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Database: UniProt
Entry: A0A098YFE0_9ACTN
LinkDB: A0A098YFE0_9ACTN
Original site: A0A098YFE0_9ACTN 
ID   A0A098YFE0_9ACTN        Unreviewed;       592 AA.
AC   A0A098YFE0;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-SEP-2017, entry version 25.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=IN07_02060 {ECO:0000313|EMBL:KGH48466.1};
OS   Modestobacter caceresii.
OC   Bacteria; Actinobacteria; Geodermatophilales; Geodermatophilaceae;
OC   Modestobacter.
OX   NCBI_TaxID=1522368 {ECO:0000313|EMBL:KGH48466.1, ECO:0000313|Proteomes:UP000029713};
RN   [1] {ECO:0000313|EMBL:KGH48466.1, ECO:0000313|Proteomes:UP000029713}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KNN45-2b {ECO:0000313|EMBL:KGH48466.1,
RC   ECO:0000313|Proteomes:UP000029713};
RA   Bukarasam K., Bull A., Girard G., van Wezel G., Goodfellow M.;
RT   "Biosystematic studies on Modestobacter strains isolated from extreme
RT   hyper-arid desert soil and from historic building.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KGH48466.1}.
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DR   EMBL; JPMX01000006; KGH48466.1; -; Genomic_DNA.
DR   RefSeq; WP_036333062.1; NZ_JPMX01000006.1.
DR   EnsemblBacteria; KGH48466; KGH48466; IN07_02060.
DR   Proteomes; UP000029713; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000029713};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029713}.
FT   DOMAIN      284    412       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      496    565       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     292    299       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   592 AA;  65821 MW;  2B38A1E6CD4BB148 CRC64;
     MADDPVDLAT VWDQARERLA SSLTPQQKAV LNLTRPLGLF EDTAVLAAPN EFTQTVLESR
     MRMVLAEALS AEIGRDIRVA VQLEDMPVPP PSPEAPRLGA EPEVRRWPTA EQDRLDQDRL
     TQDRLAHDRA SEELAARERA AHDRAAEDRA DRDRVDDGRS AFGVRTDAAR AEAWLPESGD
     GRDWSRGSAS DDQSDGGPRR LAPWDRDPGD AGRDQAPGNE GTGDRPAERS GRGGGAVPLF
     ADRRPGGLDP GLNGKYVFDS FVIGNSNRFA HAAAVAVAEA PARAYNPLFI YGDSGLGKTH
     LLHAIGHYAA RMFPNVRVRY VSTEEFTNEF INLVHSGRAE DFRRRYRDID FLLIDDIQFL
     ERAERTQEEF FHTFNTLHNA SKQIVITSDR APKKLTTLED RLRTRFEWGL ITDVQAPDLE
     TRIAILRKKA WGERLQAPDA VLEFIASKVQ TNIRELEGAL IRVTAFASLN KQPVDLALAE
     LVLKDLISDE QGPQITAAII MAATAEYFSV TMEELQGANR SRTLVNARQI AMYLCRELTE
     LSLPRIGASF GGKDHTTVMH AVKKITGLMS ERRATYTQVT ELTARIKSRA RS
//
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