ID   A0A099D649_9ACTN        Unreviewed;       295 AA.
AC   A0A099D649;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Universal stress protein {ECO:0000313|EMBL:ASU78724.1};
GN   ORFNames=CDG81_11060 {ECO:0000313|EMBL:ASU78724.1}, IL38_11115
GN   {ECO:0000313|EMBL:KGI81479.1};
OS   Actinopolyspora erythraea.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinopolysporales;
OC   Actinopolysporaceae; Actinopolyspora.
OX   NCBI_TaxID=414996 {ECO:0000313|EMBL:ASU78724.1, ECO:0000313|Proteomes:UP000215043};
RN   [1] {ECO:0000313|EMBL:KGI81479.1, ECO:0000313|Proteomes:UP000029737}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIM90600 {ECO:0000313|EMBL:KGI81479.1,
RC   ECO:0000313|Proteomes:UP000029737};
RX   PubMed=25250723;
RA   Chen D., Feng J., Huang L., Zhang Q., Wu J., Zhu X., Duan Y., Xu Z.;
RT   "Identification and Characterization of a New Erythromycin Biosynthetic
RT   Gene Cluster in Actinopolyspora erythraea YIM90600, a Novel Erythronolide-
RT   Producing Halophilic Actinomycete Isolated from Salt Field.";
RL   PLoS ONE 9:E108129-E108129(2014).
RN   [2] {ECO:0000313|EMBL:ASU78724.1, ECO:0000313|Proteomes:UP000215043}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIM 90600 {ECO:0000313|EMBL:ASU78724.1,
RC   ECO:0000313|Proteomes:UP000215043};
RA   Yin M., Tang S.;
RT   "The complete genome sequence of moderately halophilic actinomycete
RT   Actinopolyspora erythraea YIM 90600, the producer of novel erythromycin,
RT   novel actinopolysporins A-C and tubercidin.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the universal stress protein A family.
CC       {ECO:0000256|ARBA:ARBA00008791}.
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DR   EMBL; CP022752; ASU78724.1; -; Genomic_DNA.
DR   EMBL; JPMV01000018; KGI81479.1; -; Genomic_DNA.
DR   RefSeq; WP_043573145.1; NZ_KN214176.1.
DR   AlphaFoldDB; A0A099D649; -.
DR   KEGG; aey:CDG81_11060; -.
DR   eggNOG; COG0589; Bacteria.
DR   HOGENOM; CLU_049301_2_3_11; -.
DR   OrthoDB; 3404132at2; -.
DR   Proteomes; UP000029737; Unassembled WGS sequence.
DR   Proteomes; UP000215043; Chromosome.
DR   CDD; cd00293; USP_Like; 2.
DR   Gene3D; 3.40.50.620; HUPs; 2.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR006015; Universal_stress_UspA.
DR   InterPro; IPR006016; UspA.
DR   PANTHER; PTHR31964; ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR31964:SF113; USP DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00582; Usp; 2.
DR   PRINTS; PR01438; UNVRSLSTRESS.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 2.
PE   3: Inferred from homology;
FT   DOMAIN          6..146
FT                   /note="UspA"
FT                   /evidence="ECO:0000259|Pfam:PF00582"
FT   DOMAIN          159..295
FT                   /note="UspA"
FT                   /evidence="ECO:0000259|Pfam:PF00582"
SQ   SEQUENCE   295 AA;  31220 MW;  9BF3AD92C2D80011 CRC64;
     MSTTAKPVLV GIDGSPTSFE AVRWAAREAS HRSAPLRLVH ADVSALGYVP DTLGTATPDS
     TNETAREFVS DWLRDAREIA SAAAPELVVE TVVRTGSART VLLDESTTAR LVVVGSRGLG
     SFSGVVLGSV AIALTHHGQC PVAVIREPDE GAEREDLPVV VGVDGSGPGE LALRWAFDMA
     SARSAELVAV HAWHDLVVGE LWTRAQADET WESVRADEQR LLAEVLAGWR EDYPDVTVHE
     LVGYGKPARL LLDQANSARL VVVGARGRGG LAGLLLGSTS QTLLHHAPCP VVVAR
//