ID A0A099D8V1_9ACTN Unreviewed; 552 AA.
AC A0A099D8V1;
DT 07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=FAD-binding dehydrogenase {ECO:0000313|EMBL:ASU80386.1};
GN ORFNames=CDG81_21325 {ECO:0000313|EMBL:ASU80386.1}, IL38_03555
GN {ECO:0000313|EMBL:KGI82528.1};
OS Actinopolyspora erythraea.
OC Bacteria; Actinomycetota; Actinomycetes; Actinopolysporales;
OC Actinopolysporaceae; Actinopolyspora.
OX NCBI_TaxID=414996 {ECO:0000313|EMBL:ASU80386.1, ECO:0000313|Proteomes:UP000215043};
RN [1] {ECO:0000313|EMBL:KGI82528.1, ECO:0000313|Proteomes:UP000029737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM90600 {ECO:0000313|EMBL:KGI82528.1,
RC ECO:0000313|Proteomes:UP000029737};
RX PubMed=25250723;
RA Chen D., Feng J., Huang L., Zhang Q., Wu J., Zhu X., Duan Y., Xu Z.;
RT "Identification and Characterization of a New Erythromycin Biosynthetic
RT Gene Cluster in Actinopolyspora erythraea YIM90600, a Novel Erythronolide-
RT Producing Halophilic Actinomycete Isolated from Salt Field.";
RL PLoS ONE 9:E108129-E108129(2014).
RN [2] {ECO:0000313|EMBL:ASU80386.1, ECO:0000313|Proteomes:UP000215043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 90600 {ECO:0000313|EMBL:ASU80386.1,
RC ECO:0000313|Proteomes:UP000215043};
RA Yin M., Tang S.;
RT "The complete genome sequence of moderately halophilic actinomycete
RT Actinopolyspora erythraea YIM 90600, the producer of novel erythromycin,
RT novel actinopolysporins A-C and tubercidin.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP022752; ASU80386.1; -; Genomic_DNA.
DR EMBL; JPMV01000010; KGI82528.1; -; Genomic_DNA.
DR RefSeq; WP_043570038.1; NZ_KN214174.1.
DR AlphaFoldDB; A0A099D8V1; -.
DR KEGG; aey:CDG81_21325; -.
DR eggNOG; COG3573; Bacteria.
DR HOGENOM; CLU_022946_0_0_11; -.
DR OrthoDB; 9813348at2; -.
DR Proteomes; UP000029737; Unassembled WGS sequence.
DR Proteomes; UP000215043; Chromosome.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR014614; KsdD_DH.
DR PANTHER; PTHR43260; 3-KETOSTEROID-DELTA-1-DEHYDROGENASE; 1.
DR PANTHER; PTHR43260:SF1; KSDD-LIKE STEROID DEHYDROGENASE RV0785; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PIRSF; PIRSF036654; UCP036654; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 6..533
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 552 AA; 60292 MW; 41212244652BF0C2 CRC64;
MASDADVIVV GAGLAGLVAT YELTRAGRSV LLVEQENADN LGGQAHWSLG GLFLVDSPEQ
RRLGVRDSYE LALRDWTNSA AFDRPEVDYW PRRWARAYVE FAAGEKRSYL RGLGMRFMPF
VGWAERGGGT ATSHGNSVPR FHFGWGTGPE IVRVFAERVL RAERAGLVRI RYRHRVDELL
VSDGAAHGVR GGVLEPSAER RGVASSRNVV GEFEYHAQAV VVTSGGIGGD HELVRRNWPS
WLGRAPEHML TGVPAHVDGR MLDAGERAGA SVVNRDRMWH YTEGITNWDP VWPGHGIRIL
PGPSSMWLDA TGERLPAPYF PGFDNMGTLR HILGTGYDYS WFLLDQSILA KEFALSGSEQ
NPDLTDKSPR KLLSRVRKGA PGPVEAFKRH GVDFVVRDNL RDLVDGMNEL TGESLLDFGA
VRDRVAARDA EMSRPYGKDM QVSAIRAARR FVSDRAIRVA TPHGLLDDGN GPLVAVRLRP
LTRKTLGGLE TNLDSQVMRP DGSTFDGLYA AGEVAGFGGG GVHGYNALEG TFLGGCVFSG
RNAGRAIARD LI
//
